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Examining Challenges that Students Face in Learning Organic Chemistry Synthesis

open access: yesIJCER (International Journal of Chemistry Education Research), 2020
Organic chemistry is the offered after general chemistry and is the course that many find it challenging and difficult. Synthesis is first introduced in organic chemistry I course and is widely considered as one of the topics in which students struggle ...
Issa I. Salame   +2 more
doaj   +1 more source

Preparation of o-Fluorobenzoic Acid. An Elementary Organic Laboratory Experiment [PDF]

open access: yes, 1971
An experiment designed for organic chemistry students at the sophomore level is presented. The experiment, which involves no special equipment and which employs only inexpensive reagents, demonstrates the conversion of anthranilic acid to o-fluorobenzoic
Setliff, Frank L.
core   +2 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Direct synthesis of p-methyl benzaldehyde from acetaldehyde via an organic amine-catalyzed dehydrogenation mechanism

open access: yesiScience, 2021
Summary: p-Methyl benzaldehyde (p-MBA) is a class of key chemical intermediates of pharmaceuticals. Conventional industrial processes for p-MBA production involve the consecutive photochlorination, amination, and acid hydrolysis of petroleum-derived p ...
Qing-Nan Wang   +5 more
doaj  

Plasma chemistry and organic synthesis [PDF]

open access: yes
The characteristic features of chemical reactions using low temperature plasmas are described and differentiated from those seen in other reaction systems. A number of examples of applications of plasma chemistry to synthetic reactions are mentioned. The
Tezuka, M.
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back. [PDF]

open access: yesACS Org Inorg Au, 2023
Cantor EH   +5 more
europepmc   +3 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

The chemistry and use of cellulose derivatives for the study of biological systems [PDF]

open access: yes
Cellulose chemistry and applications as carrier for proteins, polymers, and organic ...
Weetall, H. H., Weliky, N.
core   +1 more source

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