Results 141 to 150 of about 1,559,720 (313)

A Dy₂ Complex Constructed by TCNQ^·− Radical Anions with Slow Magnetic Relaxation Behavior

Magnetochemistry
A centrosymmetric dinuclear complex, [Dy2(H2dapp)2(μ-OH)2(H2O)2]·4TCNQ·2CH3OH, was synthesized using the TCNQ·− radical anion (TCNQ = 7,7,8,8-tetracyanoquino-dimethane) and pentadentate nitrogen-containing Schiff base ligand (H2dapp = 2,6 ...
Xirong Wang, Shijia Qin, Xiulan Li, Wenjing Zuo, Qinglun Wang, Licun Li, Yue Ma, Jinkui Tang, Bin Zhao   +8 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Chiral covalent organic cages: Construction and chiral functions

Smart Molecules
Covalent organic cages (COCs) are three‐dimensional organic molecules with permanent cavities, known for their ordered pore structures, excellent processability, and modular design.
Si‐Dan Guo, Tianyu Jiao, Dong‐Sheng Guo, Kang Cai   +3 more
doaj   +1 more source

Comparison of the Nutritive Quality of Tomato Fruits from Organic and Conventional Production in Poland [PDF]

, 2007
Organic horticulture is generally accepted as friendly to the environment, good for crop quality and also for the consumer’s health. Recent research data has shown that organic crops under organic farming practices contained more bioactive substances ...
Hallmann, Ewelina, Rembiałkowska, Ewa
core  

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Initial soil structural development under different types of vegetation [PDF]

, 2010
In September 2007, undisturbed soil cores were taken from experimental fields in The Netherlands and in Northern Sweden that had been under different types of vegetation during four years.
Cammeraat, E.L.H., Elgersma, A., Gustavsson, A.M.   +2 more
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

NSF presentation [PDF]

Wind energy conversion research is considered in the framework of the national energy problem. Research and development efforts for the practical application of solar energy -- including wind energy -- as alternative energy supplies are assessed in: (1 ...
Morse, F. H.
core   +1 more source