Results 71 to 80 of about 1,598,383 (361)
Effect of soil properties on soil respiration in cultivated soils with varying organic matter content [PDF]
, 2023 Kristiina Lång, Viktoriia Hetmanenko
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Comparisons of organic and conventional maize and tomato cropping systems from a long-term experiment in California [PDF]
, 2005 Yield differences and trends, organic matter accumulation, and the loss of nutrients to deeper soil horizons are discussed using data from organic and conventional maize/tomato cropping systems from the Long Term Research on Agricultural Systems Project (
Bryant, Dennis +2 more
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Organic atmospheric particulate material [PDF]
, 2003 Carbonaceous compounds comprise a substantial fraction of atmospheric particulate matter (PM). Particulate organic material can be emitted directly into the atmosphere or formed in the atmosphere when the oxidation products of certain volatile organic ...
Pankow, John F., Seinfeld, John H.
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Nature CommunicationsThe β-H elimination is a crucial elementary step in transition-metal catalysis, but controlling the stereochemistry of this process has been underdeveloped.
Shaozi Sun, Shengnan Sun, Weiwei Zi
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
MoleculesTo investigate the application of novel comb-type fluorinated polymeric surfactants in suspension concentrates (SCs), we used the optimized surfactants (Comb-S 1, Comb-S 2, and Comb-S 3) as dispersants, with commercial dispersants as controls, to prepare
Jingjing Zhang +5 more
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Tracking nitrogen losses in a greenhouse crop rotation experiment in North China using the EU-Rotate_N simulation model [PDF]
, 2010 Vegetable production in China is associated with high inputs of nitrogen, posing a risk of losses to the environment. Organic matter mineralisation is a considerable source of nitrogen (N) which is hard to quantify.
Ad-hoc-Arbeitsgruppe Boden +32 more
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