Results 31 to 40 of about 491,465 (198)

The Specificity and Broad Multitarget Properties of Ligands for the Free Fatty Acid Receptors FFA3/GPR41 and FFA2/GPR43 and the Related Hydroxycarboxylic Acid Receptor HCA2/GPR109A

open access: yesPharmaceuticals, 2021
The paradigm of ligand-receptor interactions postulated as “one compound—one target” has been evolving; a multi-target, pleiotropic approach is now considered to be realistic. Novel series of 1,4,5,6,7,8-hexahydro-5-oxoquinolines, pyranopyrimidines and S-
Egils Bisenieks   +11 more
doaj   +1 more source

Influence of coffee brewing methods on the chromatographic and spectroscopic profiles, antioxidant and sensory properties

open access: yesScientific Reports, 2021
Cold brewing coffee has gained increasing popularity as a novel brewing method. A completely different flavour profile during cold brewing extraction (smooth and mild) is a result of the low-energy process, prolonged water-grind contact times and long ...
Natalia Stanek   +9 more
doaj   +1 more source

Synthesis and Evaluation of Self-Assembling Properties of 3-(3,5-Difluoro-3,5-bis((alkoxy)carbonyl)-2,6-dioxoheptan-4-yl)-1-methylpyridin-1-ium Iodides

open access: yesMolbank, 2022
A synthesis of 3-(3,5-difluoro-3,5-bis((alkoxy)carbonyl)-2,6-dioxoheptan-4-yl)-1-methylpyridin-1-ium iodides with ethyl or nonyl ester groups at positions 3 and 5 was performed. Treatment of the corresponding 2’,6’-dimethyl-1’,4’-dihydro-[3,4’-bipyridine]
Nadiia Pikun   +6 more
doaj   +1 more source

Hexathienocoronenes: Synthesis and Self-Organization [PDF]

open access: yesJournal of the American Chemical Society, 2012
Here we report hexathienocoronenes (HTCs), fully thiophene-annelated coronenes in which six double bonds in the periphery are thieno-fused. The derivatives tetrasubstituted with hexyl and dodecyl chains show a phase formation that strongly depends on the chain length.
Long Chen   +9 more
openaire   +4 more sources

Approaches to the Total Synthesis of Conduramines: A Review

open access: yesSynOpen, 2022
This review reports on the total synthesis of conduramines, which are formally derived from conduritols, mainly containing a trihydroxy aminocyclohexene core.
Hanumantharayappa Bharathkumar   +3 more
doaj   +1 more source

Conjugated Ynones in Organic Synthesis [PDF]

open access: yesChemical Reviews, 2019
This review article will consider the preparation and application of ynones in synthetic organic chemistry. Concerning the preparation of these bifunctional compounds, several methodologies starting from propargyl alcohols, acyl derivatives, both by using alkynylmetal reagents or by transition metal (mainly palladium and copper) catalyzed alkynylations,
Carmen Nájera   +2 more
openaire   +5 more sources

Human Enzymes for Organic Synthesis [PDF]

open access: yesAngewandte Chemie International Edition, 2018
AbstractHuman enzymes have been widely studied in various disciplines. The number of reactions taking place in the human body is vast, and so is the number of potential catalysts for synthesis. Herein, we focus on the application of human enzymes that catalyze chemical reactions in course of the metabolism of drugs and xenobiotics.
Winkler   +5 more
openaire   +3 more sources

Photoinduced 1,2,3,4-tetrahydropyridine ring conversions

open access: yesBeilstein Journal of Organic Chemistry, 2015
Stable heterocyclic hydroperoxide can be easily prepared as a product of fast oxidation of a 1,2,3,4-tetrahydropyridine by 3O2 if the solution is exposed to sunlight.
Baiba Turovska   +7 more
doaj   +1 more source

Solvent-free, Environmentally Benign Syntheses of Some Imines and Antioxidant Activity

open access: yesOrbital: The Electronic Journal of Chemistry, 2015
Environmentally benign, economically feasible, and solvent-free syntheses of series of imines by the condensation of a substituted hydroxynaphthyl ketone with several substituted iodoanilines under grinding approach are described.
Sainath B. Zangade   +6 more
doaj   +1 more source

Data for the cytotoxicity, self-assembling properties and synthesis of 4-pyridinium-1,4-dihydropyridines

open access: yesData in Brief, 2020
In this data file the synthetic procedures for preparation of the original 4-pyridinium-1,4-dihydropyridines (4-Py-1,4-DHP) and their parent compounds – dialkyl 2,6-dimethyl-4-(3-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylates were described. In total, 5
Klavs Pajuste   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy