Results 81 to 90 of about 883,587 (309)
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Future Frontiers in Organic Synthesis
International Journal of Bioorganic Chemistry & Molecular Biology, 2014 The role of organic synthesis to the mankind is of paramount importance since the early nineteen century [1]. In 1828, Friedrich Wöhler discovered the synthesis of urea from ammonium cyanate, marking the starting point of modern organic synthesis. Wöhler concluded to his mentor Jöns Jacob Berzelius, "I cannot, so to say, hold my chemical water and must
Leow D, Thorat V H, Santra S, Su Y
openaire +2 more sources
ChemInform Abstract: Machine‐Assisted Organic Synthesis [PDF]
ChemInform, 2015 AbstractReview: [98 refs.
Ley, Steven V +4 more
openaire +4 more sources
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Synthesis and evaluation of new high polymers for coating applications annual summary report no. 1, 26 jun. 1964 - 25 jun. 1965 [PDF]
Synthesis of organic and semi-organic polymers useful as high temperature coating ...
Breed, L. W. +3 more
core +1 more source
Active-alkali metal promoted reductive desulfurization of dibenzothiophene and its hindered analogues [PDF]
, 2005 Reductive desulfurisation of organic compounds is of importance both in organic synthesis and in industry. Benzo- and dibenzothiophenes are between the most abundant sulphur containing impurities in crude oils, and their desulfurization is a mandatory ...
Azzena, Ugo Gavino +3 more
core +2 more sources
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
Understanding Cross-Conjugation for Organic Electronics [PDF]
, 2019 Comunicación a congresopi-Conjugated organic molecules have been the focus of interest since they have been probed as potential semiconducting materials,[1] suitable for replacing the widely used silicon technologies.
Medina, Samara, Medina, Samara
core
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source