Results 101 to 110 of about 4,566,280 (295)

China-Australia: Organic opportunities [PDF]

, 2013
A century ago, China’s sustainable agricultural practices were documented and praised by US Professor of Agriculture, Franklin King, for the successful stewardship of agricultural land over four millennia.
Paull, John
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

A Review on the Scope of TFDO-Mediated Oxidation in Organic Synthesis-Reactivity and Selectivity

, 2018
Dioxiranes are three-membered strained ring peroxides that are typical archetype examples of electrophilic entities. A dioxirane-based oxidant named 3-methyl(trifluoromethyl)dioxirane (TFDO) is a fluorinated analogue of the extremely valuable oxidant ...
Shahid, Shereena,, Fattah, Tanzeela Abdul,, Rasheed, Samina,, Saeed, Aamer,, Abbas, Nadir,, Solangi, Zulfiqar Ali,, Faisal, Muhammad,, Ghumro, Sarfaraz Ali,, El-Seedi, Hesham,, Channar, Pervaiz Ali,, Larik, Fayaz Ali,, Ashraf, Zaman,   +11 more
core   +1 more source

Purchasing “Nootropics” Online: Identification and Quantification of Ingredients in Phenibut-Containing Products

Medicina
Background and Objectives: Phenibut is a central nervous system drug that is registered and used in clinical practice as a prescription medication. In recent decades, the drug has become popular as a “nootropic and cognition enhancer” because of its ...
Toms Upmanis, Eduards Sevostjanovs, Liga Zvejniece, Helena Kazoka, Vadims Kisis, Osvalds Pugovics, Maija Dambrova   +6 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Symmetric molecules with 1,4-triazole moieties as potent inhibitors of tumour-associated lactate dehydrogenase-A

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
A series of symmetric molecules incorporating aryl or pyridyl moieties as central core and 1,4-substituted triazoles as a side bridge was synthesised. The new compounds were investigated as lactate dehydro-genase (LDH, EC 1.1.1.27) inhibitors. The cancer
Abdul-Malek S. Altamimi, Ahmed M. Alafeefy, Agnese Balode, Igor Vozny, Aleksandrs Pustenko, Mohey Eldin El Shikh, Fatmah A. S. Alasmary, Sherif A. Abdel-Gawad, Raivis Žalubovskis   +8 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Organic Farming - An efficient and integrated system approach responding to pressing challenges [PDF]

, 2010
- One strict and easily understandable rule in organic farming such as the ban of synthetic fertilisers often results in a number of environmental benefits.
Stolze, Matthias, Niggli, Urs, Schader, Christian   +2 more
core   +1 more source

Synthesis and reactivity of silylmethylcyclopropanes [PDF]

, 2011
PhDSubstituted tetrahydrofurans (THFs) are common structural motifs found in natural products. The biological activity and structural complexity of these compounds makes their efficient construction with controlled regio- and stereochemistry a ...
Dunn, Jonathan
core   +2 more sources