Results 41 to 50 of about 7,126,451 (278)

Internal organisational factors enabling digitalisation in South Africa: Evidence from organisations in diverse sectors

South African Journal of Information Management
Background: Digitalisation has become a priority for organisations in their quest to improve service delivery and efficiency, and to increase their market share.
Munodani Chapano, Amanda Werner
doaj   +1 more source

Human resource management as a facilitator of a knowledge-driven organisational culture and structure for the reduction of tacit knowledge loss in South African state-owned enterprises

South African Journal of Information Management, 2022
Background: Many state-owned enterprises (SOEs) in South Africa face the serious problem of knowledge-unfriendly organisational cultures, structures and human resource management (HRM) practices that hinder the reduction of the risks associated with ...
Malefetjane Phaladi
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Low organisational justice and heavy drinking: a prospective cohort study [PDF]

, 2008
Objectives: To investigate whether low perceived organisational injustice predicts heavy drinking among employees. Methods: Data from the prospective occupational cohort study, the 10-Town Study, related to 15 290 Finnish public sector local government
Vaananen, A., Kouvonen, Anne, Pentti, Jaana, Vaananen, Ari, De Vogli, Roberto, Kivimaki, Mika, Kivimaki, M., Heponiemi, T., Väänänen, Ari, De Vogli, R, Elovainio, Marko, Linna, A, Linna, A., Vahtera, Jussi, Elovainio, M., Pentti, J, Vahtera, J, Elovainio, M, Heponiemi, T, Kivimaki, M, Vahtera, J., Kouvonen, A, Vaananen, A, Heponiemi, Tarja, Linna, Anne, De Vogli, R., Pentti, J., Kivimäki, Mika   +27 more
core   +1 more source

Business Organisational Structures of Global Companies: Use of the Territorial Model to Ensure Long-Term Growth

Social Sciences, 2018
In today’s turbulently expanding business environment, during the fourth industrial revolution, it is necessary to respond to market trends and to adapt strategy and organisational structure appropriately.
Hana Stverkova, Michal Pohludka
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Exploring barriers to innovation in higher education: An empirical investigation in Zimbabwe

South African Journal of Information Management
Background: In a competition for scarce resources, higher education institutions in developing countries have lost to other priorities. The article examines specific barriers to innovation in the higher education context.
Alfred H. Mazorodze, Peter Mkhize
doaj   +1 more source

The map and the territory. Sensemaking and sensebreaking through the organisational architecture

Problemy Zarządzania, 2014
“The map is not the territory” is a famous dictum by Alfred Korzybski that accurately describes the difficult relations between organisational structure and space.
Adam Dzidowski
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source