Results 121 to 130 of about 8,477 (218)

De-anthropomorphizing the mind: life as a cognitive spectrum in a unified framework for biological minds. [PDF]

Front Syst Neurosci
Dodig-Crnkovic G.
europepmc   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Ten simple rules for executing an inherited research plan in computational biology. [PDF]

PLoS Comput Biol
Javaheri Tehrani S, Gossmann TI.
europepmc   +1 more source

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

A five-domain functional framework for integrative physiology: a coherent and operational approach to whole-body function. [PDF]

Front Physiol
Kuang SY.
europepmc   +1 more source

Elastomeric 3D‐Printed Microenvironments Enable Nanonewton Force Measurements in Healthy and Diseased Human Pluripotent Stem Cell‐Derived Neuroepithelial Cells

Advanced Materials, EarlyView.
We present elastomeric three‐dimensional (3D) microstructures fabricated via two‐photon polymerization (2PP) and post‐processed through wet etching, for quantifying nanonewton (nN)‐scale forces applied by healthy and diseased neural cells. The mechanically characterized free‐standing beam architectures enable measurement of traction forces of ...
Pieter F. J. van Altena, Lucia Castillo Ransanz, Ruben H. Guis, Giulia Bergamaschi, Nanne J. Paauw, Urs Staufer, Vivi M. Heine, Angelo Accardo   +7 more
wiley   +1 more source

Sexual dimorphism in the nervous system: Three principles from the nematode C.elegans. [PDF]

Curr Opin Neurobiol
Portman DS, Bainbridge C, Ward ZC, Zhang J.   +3 more
europepmc   +1 more source

Multilayered Digital Microfluidic Chip for Cell‐Based Assays

Advanced Materials Interfaces, EarlyView.
A multilayered digital microfluidic (mDMF) chip architecture is introduced to improve throughput and robustness in cell‐based assays. By multilayering electrode components and dielectric layers on glass, this design significantly reduces actuation voltage, maintains reliability, and enables expansion of the operational area with minimum current leakage.
Mert Ozden, Oksana K. Savchak, Burcu Gumuscu   +2 more
wiley   +1 more source

Examining aspects of job satisfaction associated with burnout and factors related to turnover intention in genetic counselors. [PDF]

J Genet Couns
Stanley KJ, MacFarlane IM, Randall Armel S, Chitayat D, Johnstone B.   +4 more
europepmc   +1 more source

Material Before Morphology: Substrate‐Dependent Mechanical Tuning of Radular Teeth

Advanced Materials Interfaces, EarlyView.
Substrate‐dependent material tuning in Clausilia radular teeth. Closely related taxa retain a conserved gross tooth morphology, but differ in elemental composition and mechanical properties according to feeding substrate. Rock‐associated taxa show increased Ca–Si enrichment and higher stiffness and hardness, especially in the central radular region ...
Ida Lilienthal, Bernhard Hausdorf, Stanislav N. Gorb, Wencke Krings   +3 more
wiley   +1 more source