Results 91 to 100 of about 288,121 (268)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Polonya’daki İşletmelerin Sürdürülebilir Gelişmesinin Sosyal Sorumluluk Modeli

open access: yesJournal of Human and Work, 2017
Bu çalışmanın amacı Polonyalı işletmelerdeki sürdürülebilir kalkınma kavramının gelişim sürecinin belirleyicilerini ve bu işletmelerdeki başarılı sosyal sorumluluk kavramının gelişim sürecinin belirleyicilerini ve bu işletmelerdeki başarılı kurumsal ...
Ewa STAWİCKA
doaj   +1 more source

Leadership Styles and Effectiveness Among Sub-Saharan African Employees [PDF]

open access: yes, 2018
This study sought to determine whether a significant relationship exists between dimensions of transactional and transformational leadership styles and leadership effectiveness within sub-Saharan Africa.
Fadare, Samuel
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

İş Yerinde Dikkat Eksikliği ve Hiperaktivite Bozukluğuna (DEHB) Yönelik Bir Araştırma

open access: yesJournal of Human and Work, 2016
Dikkat eksikliği ve hiperaktivite bozukluğu (DEHB) yaygınlığı yaklaşık olarak çocuklukta % 8, ergenlikte % 6 ve erişkinlikte % 4 olarak bildirilmektedir. DEHB, kişilerde işe odaklanamamaya yol açmakta bu da kariyerde ilerlemeye engel olabilmektedir. DEHB
Nuray MERCAN   +3 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Sağlık Sektöründe Lider-Üye Etkileşiminin Örgütsel Vatandaşlık Davranışı Üzerindeki Etkisinin İncelenmesi

open access: yesJournal of Human and Work, 2019
Bu çalışmanın amacı; sağlık çalışanlarının lider-üye etkileşim düzeyleri alt boyutları ile ilgili değerlendirmelerinin örgütsel vatandaşlık davranışı ve alt boyutları üzerinde etki gösterip göstermediğini ortaya koymaktır. Bu kapsamda; Türkiye’nin Ankara
Duygu ÜREK, Özgür UĞURLUOĞLU
doaj   +1 more source

What is Strategic Competence and Does it Matter? Exposition of the Concept and a Research Agenda [PDF]

open access: yes, 2006
Drawing on a range of theoretical and empirical insights from strategic management and the cognitive and organizational sciences, we argue that strategic competence constitutes the ability of organizations and the individuals who operate within them to ...
Hodgkinson, Gerard P.   +1 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Leadership as a determinant of innovative behaviour [PDF]

open access: yes
In knowledge-intensive services innovative behaviour of co-workers is a critical success factor. In sectors like consultancy, research and architecture the nature of the work implies that projects are never alike.
Deanne den Hartog, Jeroen de Jong
core  

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