Läraragens i lärarlagsdiskussioner om Skolverkets allmänna råd
Forskning og Forandring, 2019 Läraragens är en viktig aspekt i talet om läraren som en professionell yrkesutövare. Läraryrkets förändring har resulterat i ökade krav av olika slag för lärarna.
Louise Frey, Anette Olin
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Management development: a new role in social change? [PDF]
, 1999 Traditional approaches to organizational change are of little use in the bid for increased innovation as they reinforce top-down predictability. An alternative approach is through the creation of pockets of good practice which act as role models of ...
Clarke, Martin, Martin Clarke
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Validation of the theoretical domains framework for use in behaviour change and implementation research [PDF]
, 2012 Background An integrative theoretical framework, developed for cross-disciplinary implementation and other behaviour change research, has been applied across a wide range of clinical situations.
Denise O’Connor +9 more
core +2 more sources
The development of a theory-based intervention to promote appropriate disclosure of a diagnosis of dementia [PDF]
, 2007 Background: The development and description of interventions to change professional practice are often limited by the lack of an explicit theoretical and empirical basis.
Foy, Robbie +6 more
core +3 more sources
Tema: Forskning som aktør i udviklingen af kultur, samfund og demokrati
Forskning og Forandring, 2019 I efterkrigstiden stod forestillingen om et fremadskridende velfærdsprojekt stærkt i Skandinavien. Det var underforstået, at et klogt og demokratisk velfærdsprojekt ville profitere af nationalstaternes gavmilde forsknings- og uddannelsespolitik.
Mia Husted +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source