Results 61 to 70 of about 288,121 (268)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Kariyer Hedef Tutarsızlık Ölçeğinin Türkçeye Uyarlanması: Geçerlik ve Güvenirlik Çalışması

Journal of Human and Work, 2020
Bu çalışmanın amacı Creed ve Hood (2015) tarafından geliştirilen Kariyer Hedef Tutarsızlık Ölçeği’nin Türkçeye uyarlanmasıdır. Çalışmada öncelikle ölçeğin Türkçeye çeviri çalışmaları yapılmış ve dil geçerliği test edilmiştir.
Faruk Caner YAM, Serdar ALKIN, Yaşar BARUT   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Factors affecting training effectiveness. A study of semiconductor wafer fabrication industry in Malaysia [PDF]

, 2008
Human Resource Development is one of the key issues for Malaysian companies since the introduction of Human Resource Development Fund (HRDF). This is the fact that rapid changes in the organizations need to develop a more focused and coherent approach to
Lin, Abdullah, Sharif, Mohmad Yazam
core  

Alternative approaches for studying shared and distributed leadership [PDF]

, 2011
Scholars hold different perspectives about leadership which are not limited to a formally appointed leader. Of the abundance of terms used to describe this phenomenon, shared and distributed are the most prevalent.
Alvarez, Arnone, Avolio, Avolio, Baligh, Balkundi, Benne, Beyerlein, Bion, Blau, Bolden, Bolden, Borgatti, Bowers, Brown, Brown, Buchanan, Burke, Burnhope, Burt, Carson, Conger, Cox, Cox, Currie, Dachler, Denis, Denis, Denyer, Drath, Drath, Engeström, Ensley, Festinger, Fletcher, Fletcher, Follett, Freeman, Gavin, Gibb, Gibb, Gnyawali, Gomez, Greenhalgh, Greenhalgh, Gronn, Gronn, Hambrick, Harris, Hartley, Heenan, Heifetz, Heifetz, Hirschhorn, Hodgson, Homans, Hosking, Houghton, Huffington, Hutchins, Katz, Kerr, Klein, Klein, Klein, Krackhardt, Leontiev, LePine, Lewin, Lewin, Lewin, Locke, Manz, Manz, Manz, Manz, Manz, Manz, Mayo, Mehra, Miller, Neck, Neumann, O'May, Pearce, Pearce, Pearce, Pearce, Pearce, Pearce, Pearce, Pearce, Petriglieri, Pye, Rescher, Rescher, Rousseau, Sandberg, Scott DeRue, Seers, Shondrick, Sivasubramaniam, Solansky, Spillane, Spillane, Spillane, Stogdill, Tranfield, Turnbull James, Uhl-Bien, Uzzi, von Bertalanffy, Vroom, Wallace, Weick, Wells, Whitehead, Whitley, Whitley, Yukl   +119 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

‘I don’t know what I’m doing. How about you?’: Discourse and identity in practitioners dealing with the survivors of childhood sexual abuse. [PDF]

, 2007
This research is based on interviews conducted with a voluntary group of health practitioners who care for the adult survivors of childhood sexual abuse in one area of Scotland.
Randall, Julian
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

İşyerinde Yalnızlığı Etkileyen Örgütsel Güven Unsurlarının Cinsiyete Göre Değişimi: Havalimanı Çalışanları Üzerine Bir Araştırma

Journal of Human and Work, 2020
Bu çalışmanın amacı örgütsel güven ile işyerinde yalnızlık arasındaki ilişkilerin araştırılmasıdır. Ayrıca örgütsel güven değişkenlerinin, işyerinde yalnızlık değişkenlerine olan etkisinin cinsiyete göre nasıl farklılaştığı, çalışmanın özgün katkısını ...
Mehmet ÖZMEN
doaj   +1 more source