Results 101 to 110 of about 259,153 (311)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Lifelong Learners Influencing Organizational Change
Studies in Business and Economics, 2018 Organizational change occurs in every organization that deals with growth and transition. Organizational leaders develop a commitment to lifelong learning throughout their careers.
Caves Lonzo
doaj +1 more source
ETIKA KERJA ISLAM, KOMITMEN ORGANISASI, SIKAP PADA PERUBAHAN ORGANISASI TERHADAP KINERJA
Jurnal Manajemen Indonesia, 2018 The subject of this study is to examine the impact of Islamic work ethics, organizational commitment, and attitude toward organizational change to work performance, where attitude toward organizational change as an intervening.
Prima Utama Wardoyo Putro
doaj +1 more source
, 2020 Purpose: The purpose of this study is to identify factors affecting an organization’s dynamic capability and, consequently, its ability to manage organizational change.
Fundin, Anders,, Bojesson, Catarina,
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Organizational Forgetting in Educational Institutions: Rethinking Organizational Change
Educational Process: International JournalBackground/purpose. This inquiry examines the phenomenon of organizational forgetting, aiming to elucidate the plausible antecedents and consequences of forgetting. Furthermore, this study examines diverse approaches and strategies that school principals
Aslıhan Uzun , İbrahim Kocabaş
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Gestão de Mudanças na Sucessão de uma Empresa Familiar – um Caso Para Ensino
Teoria e Prática em Administração, 2015 BLP is a company in the automotive branch passing through a phase of organizational change, generated by the profile of the new manager and its business model. Name change, implementation of new services and products and mainly team management changes. A
Santos, Adélia Tabaczinski dos +3 more
doaj
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source