Results 81 to 90 of about 6,765,960 (292)

Organizational choice and organizational change

open access: yes, 1997
Follows on from and develops the arguments presented in an earlier Management Decision article ‐ "No such thing as ... a ‘one best way' to manage organizational change" (Burnes, 1996a). Begins by examining Burnes' (1996b) Choice Management ‐ Change
Burnes, Bernard
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

SUSTAINABLE LEADERSHIP AND ORGANIZATIONAL SUSTAINABILITY THROUGH ORGANIZATIONAL CHANGE

open access: yesJournal of Business Paradigms, 2017
leadership and organizational sustainability, securing it through the implementation of organizational changes. In reviewing the organizational sustainability in this paper as an object of treatment are the profit organizations whose organizational ...
Cvetko Smilevsk
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

FACTORS OF ORGANIZATIONAL CULTURE CHANGE

open access: yesEkonomika, 2009
Organizational culture has a significant impact on the organization members’ life and in general it helps a company to achieve positive financial results.
Violeta Raimonda Kulvinskienė   +1 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Organizational change structures: exploring the organizational conditions for sustainable change in the agro-industry

open access: yesJournal of Organizational Change Management
PurposeThe paper starts from an observation of a discrepancy between the ambitions for sustainable change in the agro-industry and the actual changes being implemented. We offer one possible explanation by investigating the organizational structures conditioning change in this industry.Design/methodology/approachWe apply a case study methodology ...
Morten Knudsen, Sharon Kishik
openaire   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Lifelong Learners Influencing Organizational Change

open access: yesStudies in Business and Economics, 2018
Organizational change occurs in every organization that deals with growth and transition. Organizational leaders develop a commitment to lifelong learning throughout their careers.
Caves Lonzo
doaj   +1 more source

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