Results 61 to 70 of about 161,696 (263)

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

Dimensions of organizational change

open access: yesManagement : Journal of Contemporary Management Issues, 2000
A basic characteristic of business operations in developed economic environments is their continuous search for responses to very rapid changes in their broader and closer environment.
Jure Kovač
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Change and organizational change as a development strategy [PDF]

open access: yesمطالعات مدیریت بهبود و تحول, 1992
تجربیات تغییر و تحول سازمانی کشورهای در حال توسعه حاوی نکات جالب و آموزنده ای است که برای پژوهشگران این رشته و مسئولان تغییر و تحول سازمانی بسیار مفید و سازنده به نظر می رسد.
abbas mohammadzadeh
doaj  

Change, technology and higher education: are universities capable of organizational change?

open access: yesOnline Learning, 2011
Technology and change are so closely related that the use of the word innovation seems synonymous with technology in many contexts, including that of higher education.
Stephen Marshall
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Managing Organizational Change and Resistance from an Individualist vs. Collectivist Perspective [PDF]

open access: yesInternational Journal of Management, Accounting and Economics, 2015
The current research paper looked into the concept of organizational individualism and collectivism and its effect on managing change. This paper focused on the factors underlying the concepts of individualism and collectivism that influence change to ...
Ng Teng, Rashad Yazdanifard
doaj  

Psychodynamic Perspective of Organizational Change

open access: yesManagement, 2016
The complex processes and phenomena that are taking place in the contemporary world require new and adequate methods of acting also in the area of management. This means the need for a fresh approach to the process of organization development and change.
Barabasz Adela
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Teacher leadership for organizational change

open access: yesManagement : Journal of Contemporary Management Issues, 2019
The aim of this article is to test the teacher leadership initiated by teacher professional development abroad, as a factor of organisational change in a structural equation model.
Milda Damkuvienė   +2 more
doaj   +1 more source

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