Results 41 to 50 of about 259,153 (311)

HRM, organizational capacity for change, and performance: a global perspective [PDF]

open access: yes, 2012
This special issue brings together a variety of articles, each one enriching understanding about whether and how human resource management (HRM) influences organizational performance (however defined) against a backdrop of complex change.
Jonathan Crawshaw   +8 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Resisting Organizational Change

open access: yesInternational Journal of Advanced Corporate Learning (iJAC), 2015
We are continuously reminded of how change induces controversy and resistance, regardless of support. We repeatedly experience resistance in difficulties of implementation, little progress, and poor results, rather than increased productivity as anticipated.
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Barbara Czarniawska Organizational change - fashions, institutions, and translations

open access: yes, 2017
Combining neo-institutionalism, actor network theory, and Gabriel Tarde's sociology, Czarniawska considers the key driver of organizational change to be imitation but an imitation that rests on translation.
Corvellec, Hervé,   +2 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Through the professional’s eyes: transfers of care during pregnancy, childbirth and the postpartum period

open access: yesBMC Health Services Research, 2020
Background In the Netherlands, the obstetric and neonatal healthcare system consists of multiple healthcare organizations. Due to this system, transfers between healthcare professionals are inevitable.
Cherelle M. V. van Stenus   +3 more
doaj   +1 more source

The Influence of Change-Related Organizational and Job Resources on Employee Change Engagement

open access: yesFrontiers in Psychology, 2022
Employee attitudes to change are key predictors of organizational change success. In this article, change engagement is defined as the extent to which employees are enthusiastic about change, and willing to actively involve themselves in ongoing ...
Simon L. Albrecht   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A theory of organizational readiness for change

open access: yesImplementation Science, 2009
Background Change management experts have emphasized the importance of establishing organizational readiness for change and recommended various strategies for creating it.
Weiner Bryan J
doaj   +1 more source

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