Results 61 to 70 of about 1,118,027 (272)

Role of Cognitive Style of a Manager in the Development of Tourism Companies’ Dynamic Capabilities [PDF]

, 2018
Purpose – The purpose of this paper is to investigate the relationship between cognitive styles of managers working in tourism companies and dynamic capabilities of these companies. Design – The research relies on a quantitative questionnaire.
Grynko, Tatyana, Krupskyi, Oleksandr P.
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

The Role of Organizational Culture on Employee Performance Influenced by Job Satisfaction and Knowledge Sharing and Its Impact on Organizational Performance

Indonesian Interdisciplinary Journal of Sharia Economics
This study aims to analyze the influence of Organizational Culture on Employee Performance through Job Satisfaction and Knowledge Sharing, and its impact on Organizational Performance.
Dibyo Yaksaprawira, Justine Tanuwijaya, Andreas Wahyu Gunawan   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Methodology for determining influence of organizational culture to business performance

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2007
Content this article is to propose the possible methodology for quantitative measuring the organizational culture using the set of statistical methods. In view of aim we elected procedure consisting of two major sections.
Eva Skoumalová, Bohumil Minařík
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Organizational Culture and Perceived Performance: Mediation of Perceived Organizational Support and Moderation of Motivation

Administrative Sciences
This study aimed to investigate the effect of organizational culture on employee-perceived performance and whether this relationship is mediated by perceived organizational support and moderated by employee motivation.
Denise José, Ana Palma-Moreira, Manuel Au-Yong-Oliveira   +2 more
doaj   +1 more source

410 Romanian Managers’ Opinion Regarding the Place and Role of the Organizational culture in the Sustainable Development Management [PDF]

In the sustainable development management, the following important elements are present and operate: rules of conduct, values, aspirations and expectations, beliefs, specific myths, learned behavior patterns, habits, visible symbols of the company ...
H. C. Ion PETRESCU
core  

Organizational culture, leadership style and effectiveness: A case study of middle eastern construction clients [PDF]

, 2013
During the last few decades, organizational effectiveness has received a great deal of attention in many industrial sectors. As a result, a variety of models have been formulated which measure organizational performance. In the construction industry, two
Adams, Jens, Ameri, Tayebeh, Brabec, Christoph J., Krebs, Frederik C., Langner, Stefan, Li, Ning, Lucera, Luca, Machui, Florian, Salvador, Michael, Spyropoulos, George D., Strohm, Sebastian, Voigt, Monika M., Zhang, Hong   +12 more
core   +1 more source