Results 101 to 110 of about 770,724 (307)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
The Role of Organizational Communication in Enhancing Organizational Efficiency
Journal of Social Sciences and HumanitiesEffective organizational communication is a fundamental pillar of any organization's success and plays a vital role in ensuring coordination, increasing motivation, and improving the performance of the organization's personnel. This research aimed to investigate the role of organizational communication in enhancing organizational efficiency by using a ...
openaire +1 more source
PERFORMANCES AND EFFICIENCIES OF THE IRRIGATION WATER USERS’ ASSOCIATIONS IN TUNISIA [PDF]
This article analyzes the efficiency of Water Users Associations (WUA) in the Cap Bon region (Tunisia) and studies its main determinants. The analysis is performed in two stages.
Buysse, Jeroen +4 more
core +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
The Impact and Inefficiency of the Corporate Income Tax: Evidence from State Organizational Form Data [PDF]
By double taxing the income of corporate firms but not unincorporated firms, taxes can play an important role in a firm's choice of organizational form. The sensitivity of the organizational form decision to tax rates can also be used to approximate the ...
Austan Goolsbee
core
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
The state of strategic human resource measurement in Spanish banks [PDF]
, 1999 The new strategic role of Human Resource (HR) management that many academics and practitioners have been calling for requires that HR systems not only achieve operational excellence in performing their traditional activities but that they also contribute
Cabrera, Elizabeth F., Cabrera, Ángel
core +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Practices for improving labour productivity in the extractive industry
УправленецDigital transformation at the industry level makes it increasingly relevant to explore the impact of high technologies on labour organization and productivity.
Ruslan A. Dolzhenko +1 more
doaj +1 more source