Results 41 to 50 of about 770,724 (307)

Do product innovation-related activities affect downsizing decisions? An organizational efficiency perspective [PDF]

, 2017
Firms’ innovation strategy typically involves the need to shape organizational changes within work structures and routines, even those concerning employee downsizing decisions.
Estrella Ramón, Antonia, Jiménez Castillo, David, Magán Díaz, Amalia, Rondán Cataluña, Francisco Javier (Coordinador)   +3 more
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Presenting the Interpretive Structural Model of Fearless Organization Drivers in Social Security Hospitals [PDF]

Taṣvīr-i salāmat
Background. Today, psychological security, the prevalence of a supportive organizational climate, and the transformation of organizations into secure environments are of paramount importance.
Fatemeh Sadat Vahabzadeh Moghadam, Ahmad Vedadi, Karam Allah Daneshfard   +2 more
doaj   +1 more source

Customization Or Conformity? An Institutional And Network Perspective On The Content And Consequences Of TQM Adoption [PDF]

, 1997
This study develops a theoretical framework that integrates institutional and network perspectives on the form and consequences of administrative innovations.
Gulati, R., Shortell, S. M., Westphal, J. D.   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Effect of Implementing AI on Job Burnout Through the Mediating Role of Work-Life Balance in the Context of HRM

ECONOMICS
The rapid integration of Artificial Intelligence (AI) into Human Resource Management (HRM) practices has significantly transformed organizational operations.
AlOqaily Ahmad Nader, Qawasmeh Esraa Farid, Tawalbeh Jawad   +2 more
doaj   +1 more source

Theoretical and methodological matters of organizational culture [PDF]

Civilizar, 2010
This paper is concerned with Organizational Culture (OC), its components and the main techniques to study it. It states that measuring and establishing its impacts related with results, efficiency, healthy and welfare of employees are important issues ...
Claudia Eugenia Toca Torres, Jesús Carrillo Rodríguez   +1 more
doaj  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source