Results 41 to 50 of about 69,511 (259)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

When Resilience Meets Data: Unraveling the Curvilinear Path to Innovation Performance

open access: yesSAGE Open
This study examines how data-driven dynamic capabilities (DDDC) influence innovation performance through the mediating role of organizational resilience.
Haibei Luo, Xiadi Li, Yandong Chai
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Cultivating success: organizational culture’s influence on innovation and performance in SMEs

open access: yesCogent Business & Management
Organizational culture has a complex association with innovation and SME performance. This study explores the contextual associations between organizational culture, distinct innovation types, and SME performance in an under-researched African setting ...
Karikari Amoa-Gyarteng   +1 more
doaj   +1 more source

The role of green innovation on environmental and organizational performance: Moderation of human resource practices and management commitment

open access: yesHeliyon, 2023
Green innovation is an essential and burning topic for environmental and organizational performance. Therefore, this research aims to examine the effect of green innovation on environmental performance, which leads to organizational performance.
Rizwan Raheem Ahmed   +5 more
doaj   +1 more source

External relationships in the organizational innovation

open access: yesRAI Revista de Administração e Inovação, 2016
AbstractThe empiric literature regarding on technological innovation suggests that cooperation has a highly positive effect on the performance of firms’ technological innovation, however, very little is known about its impact on the organizational innovation.
Simao, Lurdes   +2 more
openaire   +2 more sources

Organizational Culture as a Factor of Organizational Innovativeness [PDF]

open access: yesBulletin of Science and Practice, 2019
Organizational culture acts as a factor of personnel management of the organization, has a controlling influence through the system of values, principles and norms of behavior. Organizational culture as a factor of organization management, various specific innovative management methods are available.
Erlygina E., Abramova Yu
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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