Results 51 to 60 of about 417,326 (307)

Organizational Innovation and Tech Innovation Persistence [PDF]

open access: yesJournal of technology management & innovation, 2020
في الاقتصادات النامية، يتم استثمار القليل في البحث والتطوير. لذلك، يُقترح أن تقوم شركات التكنولوجيا المنخفضة بتطوير قدرتها الاستيعابية وأن تكون مرتبطة من خلال شبكات السوق والشبكات المؤسسية لتحقيق استمرارية الابتكار التكنولوجي. تستخدم هذه الدراسة نموذجًا لوجستيًا ترتيبيًا مطبقًا على عينة من شركات التصنيع البيروفية، وخلصت إلى أن هناك تأثيرًا على استمرار ...
Javier Fernando Del Carpio Gallegos   +2 more
openaire   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A Dynamic Capabilities Perspective of High-Growth Firms: Organizational Aspects

open access: yesInternational Journal of Management and Economics, 2015
Drawing on interviews conducted at five Hungarian high-growth firms (HGFs), this paper discusses how dynamic capabilities shape the outcome of HGFs’ efforts to meet the managerial challenges posed by rapid growth.
Szalavetz Andrea
doaj   +1 more source

Realizing Innovations in Service Firms: new organizational forms and supporting processes [PDF]

open access: yes, 2001
This paper describes a number of innovation forms that are of special relevance to firms in the service industry. Not only technological innovations but also organizational innovations have been distinguished.
Aa, W. (Wietze) van der   +1 more
core  

Networking and innovation within the ornamental plant sector [PDF]

open access: yes, 2014
The ornamental plant cultivation could benefit from networking, as the locus of innovation is no longer the individual farm, but increasingly the network within which the farm is embedded.
Crivits, Maarten   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizational innovations management in education [PDF]

open access: yesEdukacja Ustawiczna Dorosłych, 2019
Management in education is growing in importance because of the major changes in the education system that requires efficiency and effectiveness of running.
Magda CHMIEL, Krystyna Korneta
doaj  

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