Results 61 to 70 of about 1,142,978 (287)

A framework for the definition of metrics for actor-dependency models [PDF]

open access: yes, 2004
Actor-dependency models are a formalism aimed at providing intentional descriptions of processes as a network of dependency relationships among actors. This kind of models is currently widely used in the early phase of requirements engineering as well
Franch Gutiérrez, Javier   +2 more
core   +3 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

The Impact of the Organization on the Autonomy of Agents

open access: yesInformation
In multi-agent systems (MAS), autonomy is a fundamental characteristic that enables agents to operate independently and adaptively within complex environments. However, such characteristics may cause the system to fall into undesirable situations. On the
Zouheyr Tamrabet   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Labor Pains: Change in Organizational Models and Employee Turnover in Young, High-Tech Firms [PDF]

open access: yes, 2001
[Excerpt] Organizational theories, especially ecological perspectives, emphasize the disruptive effects of change. However, the mechanisms producing these effects are seldom examined explicitly. This article ex-amines one such mechanism-employee turnover.
Baron, James N   +2 more
core   +3 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Management of Organizational Culture in the Public Institutions of Ecuador Educational Sector

open access: yesKvalita Inovácia Prosperita, 2018
Purpose: The current study has, as its fundamental objective, the conceptual analysis of organizational culture management models that could be applied in public institutions of the education sector, as well as on management models of the organizational
Mayra Mercedes Marcillo Indacochea   +2 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

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