Results 71 to 80 of about 8,245,467 (304)
The Impact of Applying Excellence Models on Enhancing Organizational Performance, An empirical study on the Information and Decision Support Center (IDSC) of the Egyptian Cabinet [PDF]
المجلة العلمية للدراسات والبحوث المالية والتجاريةThis study aimed to investigate the impact of applying excellence models on enhancing organizational performance through the empirical study on the Information and Decision Support Center (IDSC) of the Egyptian Cabinet.
Mohamed Abd El-Kader Shehab El-Din +1 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Organizational change and institutional diversity (In French) [PDF]
This paper proposes a review of the literature on the analysis of organizational change. Part 1 identifies three main factors of institutional change: competition, technological change and evolution in the institutional environment.
Marie CORIS (GREThA UMR CNRS 5113) +2 more
core
The Impact of the Organization on the Autonomy of Agents
InformationIn multi-agent systems (MAS), autonomy is a fundamental characteristic that enables agents to operate independently and adaptively within complex environments. However, such characteristics may cause the system to fall into undesirable situations. On the
Zouheyr Tamrabet +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Evaluating Alternative Models for Organizing U.S. Cyber Forces
The Cyber Defense ReviewDespite the significant investment of attention and resources, the Pentagon and armed services continue to struggle to find, train, and retain the cyber personnel needed for great power competition.
Nick Starck, Todd Arnold
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source