Results 71 to 80 of about 1,154,495 (307)

Management of Organizational Culture in the Public Institutions of Ecuador Educational Sector

open access: yesKvalita Inovácia Prosperita, 2018
Purpose: The current study has, as its fundamental objective, the conceptual analysis of organizational culture management models that could be applied in public institutions of the education sector, as well as on management models of the organizational
Mayra Mercedes Marcillo Indacochea   +2 more
doaj   +1 more source

Supporting Culture Change: Working Toward Smarter State Nursing Home Regulation [PDF]

open access: yes, 2009
Examines how the legalistic and enforcement-based regulatory approach affects nursing homes' efforts to implement culture change. Highlights regulatory partnership models that promote high performance and outlines organizational and training ...
Linda Barbarotta   +2 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The New Zealand Dairy Cooperatives’ Adaptation to Changing Market Conditions [PDF]

open access: yes
This article examines the market conditions, the strategies, and the organizational structures of agricultural cooperatives. Based on the growing literature on cooperative organizational models, it is expected that the new organizational patterns in the ...
Nilsson, Jerker, Ohlsson, Camilla
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Current development of global investment funds as a form of international business organization

open access: yesЦифровая экономика и инновации
In the modern era of globalized financial markets, the investment process has reached a qualitatively new level, transcending national borders and transforming into a complex ecosystem of international capital.
Galina A. Khmeleva, Elena S. Materova
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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