Can we evaluate network brokerage initiatives using data that are byproducts of the network broking process? [PDF]
Increasingly, development projects list social capital development and network brokerage among their objectives. How do we quantitatively evaluate such initiatives? Best practice, diff-in-diff methods may be impossible or too costly.
Abigail Barr +3 more
core
Enterprise Risk Management: Review, Critique, and Research Directions [PDF]
, 2015 © 2014 Elsevier Ltd. Many regulators, rating agencies, executives and academics have advocated a new approach to risk management: Enterprise Risk Management (ERM).
Bromiley, P +3 more
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Agile methodologies for the digital transformation of a Colombian telecommunications company
TESEA, Transactions on Energy Systems and Engineering ApplicationsContemporary business dynamics drive the adoption of agile methodologies as an effective response to rapid market evolution and the need for organizational adaptability.
Juan Sebastián Sánchez Gómez +2 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Hospital Governance, Performance Objectives, and Organizational Form
, 2001 This paper studies the governance of a sample of California hospitals. We document a number of empirical relations about hospital governance: The composition of the board of directors varies systematically across ownership types; poor performance and high administrative costs increase board turnover, with this sensitivity varying by organizational type;
Leslie Eldenburg +3 more
openaire +1 more source
Carbon-Footprint Policy Of The Top Ten Global Retailers: Contribution To Sustainable Development [PDF]
The goal of the article is to study the policy of the most prominent ten global retailers relative to the reduction in their carbon footprint. This policy is an integral part of the environmental component of the organizational policy for sustainable ...
Carmen Bălan
core
Measuring Organizational Performance in Strategic Human Resource Management: Looking Beyond the Lamppost [PDF]
, 1998 A major challenge for Strategic Human Resource Management research in the next decade will be to establish a clear, coherent and consistent construct for organizational performance.
Rogers, Edward W., Wright, Patrick M.
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source