Results 91 to 100 of about 12,344,779 (350)
National security analytical activities organizational models classification
Aspekti Publìčnogo Upravlìnnâ, 2020 The purpose of the article is to elaborate a national security analytical activities organizational models classification. The relevance of the research stems from the fact that Ukraine’s integration to the Euro-Atlantic and European security systems in ...
Vadim Sokolov
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Management ideologies and organizational spirituality: a typology [PDF]
The topic of spirituality is gaining an increasing visibility in organization studies. It is our contention that every theory of organization is a theory of organizational spirituality.
D'Oliveira, Teresa +2 more
core
Project Management - Survey Regarding the Experience and Training Requirements [PDF]
Informatică economică, 2006 The requirements specifications for a project management user centred e-learning system implied in conjunction with another specific methods and techniques, the development of a survey – based on questionnaire addressed to potential final users (see www ...
Ileana TRANDAFIR, Ana-Maria BOROZAN
doaj
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
CGIAR Resolution: Objectives, Composition and Organizational Structure
, 1971 Founding resolution on the objectives, composition and organizational structure of the Consultative Group on International Agricultural Research as articulated in May 1971 in Washington ...
CGIAR Secretariat
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
ALIGNMENT BETWEEN ORGANIZATIONAL AND INFORMATION SYSTEMS OBJECTIVES: MULTIPLE CASE STUDIES
, 2013 This paper presents an exploratory study on the alignment between organizational objectives, as formalized in the business plans, and the information provided by Information Systems (IS) in order to monitor these objectives.
Hoppen, Norberto +3 more
core
A Creative Way to Introduce Aligned Strategic Decisions Making in Portfolio Management Process [PDF]
مطالعات مدیریت راهبردی, 2011 Project portfolio management helps organizations to plan, evaluate, prioritize and select the projects as managerial new pattern. This pattern confirms achieving the organizational strategic objectives through integrated management while observing ...
Ahmad Ali Yazdanpanah +2 more
doaj