Results 61 to 70 of about 873,668 (288)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Modelos Organizacionais das Bibliotecas Municipais de Lisboa

open access: yesPáginas a&b, 2020
Organizational management requires sustained strategies to continuously achieve effective and efficient actions. Its implementation implies planning practices, ways of structuring key organizational elements and mechanisms for both monitoring and ...
Filipe Casimiro   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Study of effective factors on the rate of citizen\'s trust to the municipal performance of Sari city [PDF]

open access: yesتحقیقات کاربردی علوم جغرافیایی, 2023
Many social researchers and experts has emphasized on the importance of confidence in the society. Municipality as one of the biggest social organizations can enjoy more productivity and efficiency when attracts citizens' confidence as a social and ...
shahram mollania jelodar   +3 more
doaj  

Creativity, Free Expression, and Professionalism: Value Conflicts in U.S. Community Radio [PDF]

open access: yes, 2006
This study investigates how the values of free expression and professionalism provide the basis for interpersonal and organizational conflict in U.S. community radio stations, and shape divergent approaches to audience service. Using qualitative methods,
Huntsberger, Michael
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Social Cooperatives' Ways of Operation Activity in Poland — Some Features of Theory and Practice [PDF]

open access: yes, 2010
The paper is composed of three parts. Its first part contains deliberations about the concept itself and objectives of the social cooperative. They are presented against a wider background of human and social capital creation by enterprises.
Duraj Jan
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Developing a model for alignment between individual and organizational performance management and organizational objectives

open access: yesJournal of Human Resource Management, 2018
The success of each organization depends on its ability to evaluate its performance and then use the results of performance evaluation to enhance its efficiency. The present study is aimed at developing a model for investigating the relationships between
Shapoor Sherafat, Ahmad Ali Khaef Elahi
doaj  

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