Results 71 to 80 of about 1,157,683 (306)

Do product innovation-related activities affect downsizing decisions? An organizational efficiency perspective [PDF]

open access: yes, 2017
Firms’ innovation strategy typically involves the need to shape organizational changes within work structures and routines, even those concerning employee downsizing decisions.
Estrella Ramón, Antonia   +3 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Digital Сompetence of Russian School Teachers

open access: yesПсихологическая наука и образование, 2015
This article presents the results of digital competence study in different types of pedagogical stuff of Russian educational organization (informatics teachers – 140 participants, subject teachers – 145 participants, other categories – 112 participants ...
Soldatova G.U., , Shlyapnikov V.N.,
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Assessing Consumer Behavior in the Wine Industry and Its Consequences for Wineries: A Case Study of a Spanish Company

open access: yesFrontiers in Psychology, 2019
The widening gap between production and domestic consumption has led Spain to become the country with the largest volume of wine exports, of which it has a global market share of 20.5%.
Rosa M. Muñoz   +2 more
doaj   +1 more source

A model for enterprises’ environmental scanning [PDF]

open access: yes
Today’s environment determines companies to use scanning activities in order to seize the opportunities and to avoid the threats. Individual factors and organizational factors influence the scanning behavior.
Catalin Mihail Barbu, Tudor Nistorescu
core  

Exploring the relationship between knowledge management and organizational learning via fuzzy cognitive mapping [PDF]

open access: yes, 2008
The normative literature within the field of Knowledge Management has tended to concentrate on techniques and methodologies for codifying knowledge. Similarly, the literature on organizational learning, focuses on aspects of those knowledge that are ...
Irani, Z, Sharif, A M
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Conversação entre Abordagens da Estratégia em Organizações: Escolha Estratégica, Cognição e Instituição [PDF]

open access: yesRAC: Revista de Administração Contemporânea, 2010
This paper was written with the objective of checking on the treatment given to the concept of organizational strategy within each of the strategic choice, cognitive and institutional approaches.
Valéria S. da Fonseca   +1 more
doaj  

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