Results 111 to 120 of about 1,348,493 (267)
The Optimal Design of Fallible Organizations: Invariance of Optimal Decision Criterion and Uniqueness of Hierarchy and Polyarchy Structures [PDF]
We present a general framework to study the project selection problem in an organization of fallible decision-makers. We show that when the organizational size and the majority rule for project acceptance are optimized simultaneously, the optimal quality
Winston T H Koh
core
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Networked Organizational Structure of Enterprise Information Security Management Based on Digital Transformation and Genetic Algorithm. [PDF]
Front Public Health, 2022 Di Z, Liu Y, Li S.
europepmc +1 more source
Screening, competition and (de)centralization [PDF]
Competition;Organizational Structure;Decentralization;Centralization;organization and ...
Hendrikse, G.W.J.
core +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Organizational Structure Change and Hybridity: Enhancing Uncertainty as a Response to Competing and Changing Institutional Logics. [PDF]
Front Psychol, 2022 Liu L, Zhang C.
europepmc +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Journal of Civil Engineering and ManagementDigital transformation is a pathway to improve productivity in the construction sector, but organizational structures still need more adaptation. There are no fully developed models at the level of factors and evidence between organizational structures ...
Cristian C. Osorio-Gómez +3 more
doaj +1 more source
A survey of organizational structure and operational practices of elite youth football academies and national federations from around the world: A performance and medical perspective. [PDF]
Front Sports Act Living, 2022 Gregson W +10 more
europepmc +1 more source
Enhancing the Capability of Central Finance Agencies [PDF]
A well-organized and effective finance ministry and its associated central finance agencies (CFAs) are essential to good fiscal outcomes. Recent studies of CFAs in selected low-income countries demonstrate that their organizational structure varies ...
Allen, Richard, Grigoli, Francesco
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