Results 61 to 70 of about 342,219 (315)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Investigating the Relationship between Work-Family Conflict (WFC) and Organizational Intelligence with the Mediating Role of Perceived Organizational Support and Job Performance of Nurses in Golestan Hospital of Ahvaz City, Khuzestan, Iran [PDF]

open access: yesPreventive Care in Nursing and Midwifery Journal, 2019
Background: Nurses constitute one of the most important occupational groups and pillars in organizations who provide healthcare services in all countries.
Narges Rasouli   +3 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Current status and influencing factors of job crafting ability in operating room senior nurses: a cross-sectional study

open access: yesFrontiers in Psychology
BackgroundSenior nurses are pivotal to healthcare quality but face heightened burnout and career stagnation, especially in high-stakes environments like the operating room (OR).
Qiwen Lian   +4 more
doaj   +1 more source

The Effect of Organizational Support on Organizational Commitment

open access: yesThe Anthropologist, 2014
This research examines the effect of organizational support for teachers on their organizational commitment. The data was collected from 819 primary school teachers in seven cities from every geographical regions of Turkey. In the research, the two scales administered are "Perceived Organizational Support Scale (POSS)" and "Teachers' Organizational ...
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Exploring the Mechanisms Linking Transformational Leadership, Perceived Organizational Support, Creativity, and Performance in Hospitality: The Mediating Role of Affective Organizational Commitment

open access: yes, 2022
Integrating leadership and creativity theories, this study proposed and examined a model linking transformational leadership, perceived organizational support, affective organizational commitment, creativity, and performance. Structural equation modeling
Wang, Chung-Jen, Chung-Jen Wang
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Drivers of innovative behaviors: The moderator roles of perceived organizational support and psychological empowerment

open access: yes, 2017
Innovative behaviors are one of the most important factors that affect the competitiv performance of organizations. Although there are numerous studies in the literature which try to determine the antecedents of innovative behaviors. there are still gaps
Yildiz, Bora   +2 more
core   +1 more source

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