Results 81 to 90 of about 691,724 (295)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Organizational Learning – Desperately Seeking Theory?

open access: yes, 1999
Concepts of organizational learning abound in the literature. There has been an increasing diversity of attempts at classification, but an integrated theory is still missing. To provide some tentative answers as to why theory development in organizational learning has made such little progress, a number of requirements for theory-building will be ...
openaire   +3 more sources

Missing Variables in Theories of Strategic Human Resource Management: Time, Cause, and Individuals [PDF]

open access: yes, 2005
Much progress has been made with regard to theory building and application in the field of Strategic Human Resource Management (HRM) since Wright and McMahan’s (1992) critical review.
Haggerty, John J., Wright, Patrick M.
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

New Ideas about Leadership at Work in the Workplace

open access: yesRevista Transilvană de Ştiinţe Administrative, 2002
This study examines the impact of managerial leadership theories on the way mangers in organizations across US perceive and define their organizational performance. The analysis focuses on the model of managerial efficiency described by the open systems,
Mirela NEMEȘ
doaj  

Stylistic Creativity in the Utilization of Management Tools [PDF]

open access: yes
We analyze the role of management instruments in the development of collective activity and in the dynamics of organization, recurring to pragmatic and semiotic theories.
Lorino, Philippe
core   +1 more source

ISO 9001 Quality Management Systems through the Lens of Organizational Culture [PDF]

open access: yes, 2015
Both managers and scholars have convictions about the organizational approaches that best support organizational performance of the respective organizations and its Quality Management Systems.
Fonseca, Luís Miguel
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

A Glance at Terrorist Organizations from the Perspective of Organizational Theories

open access: yesCumhuriyet Üniversitesi İktisadi ve İdari Bilimler Dergisi, 2013
The problem of conceptualizing terrorist organization is still a controversial issue, even though it has been taken place in the literature heavily.
Sefer Yılmaz
doaj  

How does the external context affect an implementation processes? A qualitative study investigating the impact of macro-level variables on the implementation of goal-oriented primary care

open access: yesImplementation Science
Background Although the importance of context in implementation science is not disputed, knowledge about the actual impact of external context variables on implementation processes remains rather fragmented. Current frameworks, models, and studies merely
Ine Huybrechts   +5 more
doaj   +1 more source

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