Results 81 to 90 of about 691,724 (295)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Organizational Learning – Desperately Seeking Theory?
Concepts of organizational learning abound in the literature. There has been an increasing diversity of attempts at classification, but an integrated theory is still missing. To provide some tentative answers as to why theory development in organizational learning has made such little progress, a number of requirements for theory-building will be ...
openaire +3 more sources
Missing Variables in Theories of Strategic Human Resource Management: Time, Cause, and Individuals [PDF]
Much progress has been made with regard to theory building and application in the field of Strategic Human Resource Management (HRM) since Wright and McMahan’s (1992) critical review.
Haggerty, John J., Wright, Patrick M.
core +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
New Ideas about Leadership at Work in the Workplace
This study examines the impact of managerial leadership theories on the way mangers in organizations across US perceive and define their organizational performance. The analysis focuses on the model of managerial efficiency described by the open systems,
Mirela NEMEȘ
doaj
Stylistic Creativity in the Utilization of Management Tools [PDF]
We analyze the role of management instruments in the development of collective activity and in the dynamics of organization, recurring to pragmatic and semiotic theories.
Lorino, Philippe
core +1 more source
ISO 9001 Quality Management Systems through the Lens of Organizational Culture [PDF]
Both managers and scholars have convictions about the organizational approaches that best support organizational performance of the respective organizations and its Quality Management Systems.
Fonseca, Luís Miguel
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
A Glance at Terrorist Organizations from the Perspective of Organizational Theories
The problem of conceptualizing terrorist organization is still a controversial issue, even though it has been taken place in the literature heavily.
Sefer Yılmaz
doaj
Background Although the importance of context in implementation science is not disputed, knowledge about the actual impact of external context variables on implementation processes remains rather fragmented. Current frameworks, models, and studies merely
Ine Huybrechts +5 more
doaj +1 more source

