Results 11 to 20 of about 726 (96)
DNA-Binding Properties of Iridium(III) Complexes Encompassing Design, Function and Biophysical Assessments. [PDF]
ChemphyschemThis review describes the biophysical techniques used to investigate DNA‐binding phenomena and the progress made so far in the application of iridium(III) complexes for this purpose. Ir(III) complexes offer myriad opportunities in the design and study of DNA‐binding agents and discussed examples are contextualised with complementary studies in ...
Alkhaibari IS, Buurma NJ, Pope SJA.
europepmc +2 more sources
Flavin Catalysts in Organic Synthesis
Angewandte Chemie, EarlyView.Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
wiley +2 more sources
The preferred conformation of erythro- and threo-1,2-difluorocyclododecanes
Beilstein Journal of Organic Chemistry, 2012 Cyclododecane adopts a square-like structure with corner and edge CH2 groups. In this study erythro- and threo-1,2-difluorocyclododecanes were prepared to explore whether the two vicinal C–F bonds, with different relative configurations, preferably ...
Yi Wang +4 more
doaj +1 more source
Prins fluorination cyclisations: Preparation of 4-fluoro-pyran and -piperidine heterocycles
Beilstein Journal of Organic Chemistry, 2010 The Prins reaction was investigated using BF3·OEt2 as a Lewis acid. It has been recently demonstrated, that if BF3·OEt2 is used in stoichiometric amounts then these reactions generate fluorinated products where the BF3·OEt2 contributes fluoride ion to ...
Guillaume G. Launay +2 more
doaj +1 more source
Three step synthesis of single diastereoisomers of the vicinal trifluoro motif
Beilstein Journal of Organic Chemistry, 2009 A three step route to single diastereoisomers of the vicinal trifluoromethyl motif is described. The route starts from either syn- or anti-α,β-epoxy alcohols and takes a direct approach in that each of the three steps introduces a fluorine atom in a ...
Vincent A. Brunet +2 more
doaj +1 more source
On the Ability of Bismuth to Couple Weakly Coordinating Anions
Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.Motivated by the growing number of catalytic processes based on high‐valent Bi, we investigated in silico the reductive elimination step responsible for the coupling of weakly coordinating anions. Relativistic contributions appeared to be decisive to the electronic description of the intermediates involved in this process.
Lucas Mele +3 more
wiley +2 more sources
Direct Regioselective para‐Fluorination via I(I)/I(III) Catalysis
Angewandte Chemie International Edition, EarlyView.A direct, para‐selective fluorination by I(I)/I(III) catalysis is disclosed that does not require substrate pre‐functionalization. This strategy leverages the Leonard link inherent to phenylpropanoate and phenylpropanamides to promote a spirocyclization/para‐selective sequence. The C3‐side chain maps onto a range of common drug scaffolds and allows the
Christoph Roblick +5 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis +2 more
wiley +2 more sources
Nickel‐Catalyzed Reductive Cross‐Coupling of Xanthate Esters With Aryl and Alkenyl Iodides
Chemistry – A European Journal, EarlyView.A nickel‐catalyzed reductive cross‐coupling of xanthate esters and aryl/alkenyl iodides is reported without the need for separate activators for the xanthate esters. The reaction utilizes a relatively low catalyst loading. Diarylmethanes with a good functional group variety can thus be synthesized indirectly from the corresponding benzylic alcohols ...
Felix Vöhringer +4 more
wiley +1 more source
Photochemical and Thermal Activation of a Diarylbismuth Azide
Chemistry – A European Journal, EarlyView.We report the synthesis and characterization of a novel diarylbismuth azide and its divergent reactivity upon thermal or photochemical activation. These findings contribute expanding the reactivity landscape of heavy pnictogen compounds and sets the basis for further investigations. ABSTRACT Azides are widely employed in synthesis as convenient nitrene
Giacomo Pugliese +5 more
wiley +1 more source