Results 151 to 160 of about 10,956 (235)

Effective and Practical Stereoselective Synthesis of Nutlins Precursors by Immobilization of Privileged Chiral Mono‐Amidine Catalyst

Advanced Synthesis &Catalysis, Volume 367, Issue 9, May 6, 2025.
Abstract A strategy for the immobilization of Johnston's Mono(AMidine) catalyst (MAM) onto polystyrene, silica and hybrid silica‐polystyrene nanoparticles is presented. The catalyst activity was evaluated in the stereoselective aza‐Henry reaction leading to the pivotal β‐amino nitroalkane precursors of the anti‐cancer agents Nutlins (with Nutlin‐3a as ...
Sofia Toldo, Lorenzo Poletti, Graziano Di Carmine, Olga Bortolini, Carmela De Risi, Simona Felletti, Greta Compagnin, Alessandro Massi, Daniele Ragno   +8 more
wiley   +1 more source

127I Solid‐State NMR Spectroscopy of Organic Periodates Featuring Halogen Bonded IO4− ⋅ ⋅ ⋅ IO4− Adducts

ChemPhysChem, Volume 26, Issue 9, May 5, 2025.
A series of periodate salts, both with and without halogen bonds, were investigated using 127I solid‐state NMR at three different magnetic fields. The presence of halogen bonds affects the resulting 127I SSNMR spectra, helping in the discrimination between halogen bond‐based adducts and control samples. Abstract Hydroxyanions and oxyanions can overcome
Roberta Beccaria, Andrea Pizzi, Giuseppe Resnati, David L. Bryce   +3 more
wiley   +1 more source

Switching mesoionic carbene-organocatalysis from radical to ionic pathway through base-controlled formation of Breslow intermediates <i>versus</i> Breslow enolates. [PDF]

Chem Sci
Jiao J, Zhang Z, Lu G, Huang S, Bian Y, Gao F, Bertrand G, Yan X.   +7 more
europepmc   +1 more source

Asymmetric Counteranion-Directed Halogen Bonding Catalysis. [PDF]

J Am Chem Soc
Reinhard DL, Iniutina A, Reese S, Shaw T, Merten C, List B, Huber SM.   +6 more
europepmc   +1 more source

Enantioselective α-heterofunctionalization reactions of catalytically generated C1-Lewis base enolates

Tetrahedron Chem
Chiral Lewis base (LB) organocatalysis has emerged as a powerful covalent catalysis concept which allows for highly selective asymmetric C–C and C-heteroatom bond formations.
Magdalena Piringer, Lotte Stockhammer, Lukas Vogl, David Weinzierl, Paul Zebrowski, Mario Waser   +5 more
doaj  

N-Heterocyclic Carbene Organocatalysis Enabled Modular Synthesis of Fluorinated Isoflavonoids to Suppress Proliferation and Migration in Breast Cancer Cells. [PDF]

Adv Sci (Weinh)
Liu YQ, Fu LL, Hong LH, Kou XX, Zhang X, Zeng R, Zhen YQ, Han B, Li JL.   +8 more
europepmc   +1 more source

Beyond symmetric self-assembly and effective molarity: unlocking functional enzyme mimics with robust organic cages. [PDF]

Beilstein J Org Chem
Andrews KG.
europepmc   +1 more source

Influence of the Mesoporosity of Silica Carrier Materials on the Performance of an Immobilized Organocatalyst in Heterogeneous Catalysis. [PDF]

ACS Appl Mater Interfaces
Trommer A, Hessling J, Schreiner PR, Schönhoff M, Smarsly BM.   +4 more
europepmc   +1 more source

Recent Advances in the Enantioselective Organocatalytic [4+2] Cycloadditions. [PDF]

Molecules
Bauer T.
europepmc   +1 more source

Asymmetric Synthesis of 2-Arylethylamines: A Metal-Free Review of the New Millennium. [PDF]

Molecules
Manchado A, García-González Á, Nieto CT, Díez D, Garrido NM.   +4 more
europepmc   +1 more source