Reagents for Selective Fluoromethylation: A Challenge in Organofluorine Chemistry [PDF]
Angewandte Chemie - International Edition, 2020 AbstractThe introduction of a monofluoromethyl moiety has undoubtedly become a very important area of research in recent years. Owing to the beneficial properties of organofluorine compounds, such as their metabolic stability, the incorporation of the CH2F group as a bioisosteric substitute for various functional groups is an attractive strategy for ...
Marco Reichel, Konstantin Karaghiosoff
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Palladium-Mediated Organofluorine Chemistry [PDF]
Advances in Organometallic Chemistry, 2014 Producción ...
Ana C Albeniz, Juan A Casares
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Contemporary synthetic strategies in organofluorine chemistry [PDF]
Nature Reviews Methods Primers, 2021 Fluorinated molecules have a wide range of applications and are used as medicines, agrochemicals and refrigerants and in smartphone liquid crystal displays, photovoltaic solar cells, Teflon tapes and the coatings of textiles and buildings. Fluorination and fluoroalkylation — incorporation of a trifluoromethyl, difluoromethyl or monofluoromethyl group —
Robert Britton +7 more
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FluoBase: a fluorinated agents database [PDF]
Journal of CheminformaticsOrganofluorine compounds, owing to their unique physicochemical properties, play an increasingly crucial role in fields such as medicine, pesticides, and advanced materials.
Rafal Mulka +7 more
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Copper difluorocarbene-involved catalytic gem-difluoropropargylation [PDF]
Nature CommunicationsThe use of metal for catalytic difluorocarbene transfer reactions has long been hindered by the lack of understanding of metal difluorocarbene chemistry, despite the potential implications for medicinal chemistry and advanced materials science.
Xin Zeng +3 more
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Organofluorine chemistry: Difluoromethylene motifs spaced 1,3 to each other imparts facial polarity to a cyclohexane ring [PDF]
Beilstein Journal of Organic Chemistry, 2016 Mathew J Jones +2 more
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Reasons why life on Earth rarely makes fluorine-containing compounds and their implications for the search for life beyond Earth [PDF]
Scientific ReportsLife on Earth is known to rarely make fluorinated carbon compounds, as compared to other halocarbons. We quantify this rarity, based on our exhaustive natural products database curated from available literature.
Janusz J. Petkowski +2 more
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Combustion ion chromatography for extractable organofluorine analysis
iScience, 2021 Summary: Combustion ion chromatography (CIC) has found a role in environmental analytical chemistry for fluorine content analysis. It is used for extractable organofluorine (EOF) analysis to evaluate perfluoroalkyl and polyfluoroalkyl substances (PFASs ...
Rudolf Aro +4 more
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Organofluorine chemistry: applications, sources and sustainability [PDF]
Green Chemistry, 2015 Fluorine is an essential element for life in the developed world that impacts hugely on the general public because many pharmaceuticals, agrochemicals, anaesthetics, materials and air conditioning materials owe their important properties to the presence of fluorine atoms within their structures.
Harsanyi, Antal; Sandford, Graham
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Copper-promoted/copper-catalyzed trifluoromethylselenolation reactions
Beilstein Journal of Organic Chemistry, 2020 Copper catalysis and, more generally, copper chemistry are pivotal for modern organofluorine chemistry. Major advances have been made in the field of trifluoromethylselenolations of organic compounds where copper catalysis played a crucial role.
Clément Ghiazza, Anis Tlili
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