Results 21 to 30 of about 2,771,586 (165)
Molecules, 2022 A reagent-controlled highly stereoselective reaction between (S)-difluoromethyl phenyl sulfoximine 1 and imines is reported, and this synthetic method provides a variety of enantiomerically enriched α-difluoromethyl amines. The main pros of this approach
Qinghe Liu +3 more
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Oxidation of difluorocarbene and subsequent trifluoromethoxylation
Nature Communications, 2019 Difluorocarbene is a versatile and efficient intermediate for fluorine incorporation. Here, the authors show that difluorocarbene can be oxidized to carbonyl fluoride and this process is confirmed in 18O-trifluoromethoxylation reactions, by observation ...
Jiao Yu +4 more
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Nickel-catalyzed alkyl-arylation of 3,3,3-trifluoropropene
Communications Chemistry, 2022 3,3,3-Trifluoropropene is a cost-efficient precursor for the preparation of trifluoromethylated compounds, but limited methods for its efficient transformation have been reported.
Chang Xu +3 more
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Beilstein Journal of Organic Chemistry, 2014 Background: 1,1-Difluoroalkenes cannot only be used as valuable precursors for organic synthesis, but also act as bioisosteres for enzyme inhibitors. Among various methods for their preparation, the carbonyl olefination with difluoromethylene phosphonium
Fei Wang +3 more
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Beilstein Journal of Organic Chemistry, 2023 A visible-light-induced nickel-catalyzed cross coupling of alkyl carboxylic acids with N-trifluoroethoxyphthalimide is described. Under purple light irradiation, an α-hydroxytrifluoroethyl radical generated from a photoactive electron donor–acceptor ...
Feng Chen +4 more
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Organofluorine Compounds in Biology and Medicine
, 2015 This book covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly ...
Reddy, V. Prakash +2 more
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Flow microreactor synthesis in organo-fluorine chemistry
Beilstein Journal of Organic Chemistry, 2013 Organo-fluorine compounds are the substances of considerable interest in various industrial fields due to their unique physical and chemical properties.
Hideki Amii +2 more
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The xanthate route to organofluorine derivatives. A brief account
, 2016 International audienceThe present account summarises routes to organofluorine derivatives based on the chemistry of xanthates developed in the author's laboratory.
Zard, Samir Z
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, 2021 Per- and polyfluoroalkyl substances (PFAS) have been linked to a range of negative health and environmental effects. Regulations limiting and/or banning the use of some of the legacy compounds have been introduced. Consequently, the production and use of
Aro, Rudolf
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Beilstein Journal of Organic Chemistry, 2008 We present a mechanistic investigation of Pd-catalyzed allylic substitution of cyclic gem-difluorinated carbonates 1 and 4, previously employed in the synthesis of 3',3'-difluoro-2'-hydroxymethyl-4',5'-unsaturated carbocyclic nucleosides in 17 steps. The
Jun Xu, Xiao-Long Qiu, Feng-Ling Qing
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