Results 31 to 40 of about 1,384 (194)

A Clean and Selective Radical Homocoupling Employing Carboxylic Acids with Titania Photoredox Catalysis

, 2014
A titania photoredox catalysis protocol was developed for the homocoupling of C-centered radicals derived from carboxylic acids. Intermolecular reactions were generally efficient and selective, furnishing the desired dimers in good yields under mild ...
Manley, David W., Walton, John C.
core   +1 more source

Understanding the mechanism of Pd-catalyzed allylic substitution of the cyclic difluorinated carbonates

Beilstein Journal of Organic Chemistry, 2008
We present a mechanistic investigation of Pd-catalyzed allylic substitution of cyclic gem-difluorinated carbonates 1 and 4, previously employed in the synthesis of 3',3'-difluoro-2'-hydroxymethyl-4',5'-unsaturated carbocyclic nucleosides in 17 steps. The
Jun Xu, Xiao-Long Qiu, Feng-Ling Qing
doaj   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

Enantioselective nucleophilic difluoromethylation of aromatic aldehydes with Me3SiCF2SO2Ph and PhSO2CF2H reagents catalyzed by chiral quaternary ammonium salts

Beilstein Journal of Organic Chemistry, 2008
BackgroundAlthough the nucleophilic difluoromethylation of aldehydes, ketones, and imines has been realized with PhSO2CF2H and related reagents, there are still no reports on the enantioselective nucleophilic reactions.ResultsWith a chiral quaternary ...
Chuanfa Ni, Fang Wang, Jinbo Hu
doaj   +1 more source

Photocatalytic Synthesis of Pentafluorosulfanyl Ketones, Acetals, and BCP Motifs Utilizing SF6

Advanced Science, EarlyView.
A photocatalytic single electron reduction strategy is reported for the activation and valorization of sulfur hexafluoride (SF6), a potent greenhouse gas. Under mild conditions, SF6 is reduced to generate pentafluorosulfanyl (SF5) radicals, enabling direct access to pentafluorosulfanyl ketones, acetals, and BCP motifs.
Chen‐Hui Jiang, Haoran Xu, Yi‐Gang Yang, Xuan Nie, Meng‐Meng Zheng, Yue Zhao, Ya‐Wen Zuo, Wei‐Ran Ren, Shan Zhu, Ruo‐Xing Jin, Xiao‐Song Xue, Xi‐Sheng Wang   +11 more
wiley   +1 more source

The Recent Development of Organofluorine Chemistry in China: Asymmetric Construction of Stereogenic Trifluoromethyl-substituted Carbon Centers

CHIMIA, 2011
The stereospecific incorporation of the trifluoromethyl group into an organic compound has attracted considerable attention and significant progress has been achieved in the past decade.
Lele Wen, Qilong Shen, Long Lu
doaj   +1 more source

KPT330 improves Cas9 precision genome- and base-editing by selectively regulating mRNA nuclear export

Communications Biology, 2022
The FDA-approved anti-cancer drug, KPT330, can indirectly inhibit Cas9 by interfering with Cas9 mRNA nuclear export and help reduce off-target editing in cells.
Yan-ru Cui, Shao-jie Wang, Tiancheng Ma, Peihong Yu, Jun Chen, Taijie Guo, Genyi Meng, Biao Jiang, Jiajia Dong, Jia Liu   +9 more
doaj   +1 more source

Adsorption of Forever Chemical Pollutants: The Physical Chemistry of PFAS Near Surfaces

Advanced Science, EarlyView.
Current adsorption‐based remediation techniques for removing per‐ and polyfluoroalkyl substances (PFAS) from water are limited by knowledge gaps on PFAS behavior near solid surfaces. This review provides a state of the art on theoretical and experimental aspects of PFAS adsorption.
Nada Ben Amor, Daniela Bauer, Benjamin Braconnier, Benoit Coasne   +3 more
wiley   +1 more source

Electrophilic fluorinatíon of ethers and deactivated benzene derivatives [PDF]

, 2005
Chapter 1 - Chapter 1 provides a literature review of the relevant topics for this thesis in organofluorine chemistry: effect of fluorine as a substituent on the molecule, synthesis of C-F bond from C-H bond using electrophilic reagents with discussions ...
Trmčić, Jelena
core  

Fluorous Reverse Phase Silica Gel. A New Tool for Preparative Separations in Synthetic Organic and Organofluorine Chemistry

, 2001
Fluorous reverse phase silica gel, or silica gel with a fluorocarbon bonded phase, can be readily prepared by standard techniques, but shows unusual separation features. This silica gel separates primarily by fluorine content.
Curran, Dennis P
core   +1 more source