Results 111 to 120 of about 137,132 (345)

Baicalein Alleviates Lithium-Pilocarpine-Induced Status Epilepticus by Regulating DNMT1/GABRD Pathway in Rats

Organogenesis
Background Epilepsy is a common disease of the nervous system. Recent advances in epigenetics have revealed DNA methylation as a key mechanism in epilepsy pathogenesis, particularly through dysregulation of GABAergic signaling.
Zhenggang Wu, Jing Liu, Deju Yin, Jing Huang, Yujing Huang, Pengfei Wang   +5 more
doaj   +1 more source

Transcription factor-mediated direct cellular reprogramming yields cell-type specific DNA methylation signature

Scientific Reports, 2023
Direct reprogramming, inducing the conversion of one type of somatic cell into another by the forced expression of defined transcription factors, is a technology with anticipated medical applications.
Kenichi Horisawa, Shizuka Miura, Hiromitsu Araki, Fumihito Miura, Takashi Ito, Atsushi Suzuki   +5 more
doaj   +1 more source

Cytoskeleton and plant organogenesis [PDF]

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2002
The functions of microtubules and actin filaments during various processes that are essential for the growth, reproduction and survival of single plant cells have been well characterized. A large number of plant structural cytoskeletal or cytoskeleton–associated proteins, as well as genes encoding such proteins, have been identified.
Benedikt, Kost, Yi-Qun, Bao, Nam-Hai, Chua   +2 more
openaire   +2 more sources

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

Journal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes, Claudia Camaioni, João B. Augusto, Kristopher Knott, Ellie Quinn, Gabriella Captur, Andreas Seraphim, George Joy, Petros Syrris, Perry M. Elliott, Saidi Mohiddin, Peter Kellman, Hui Xue, Luis R. Lopes, James C. Moon   +14 more
wiley   +1 more source

Tissue Culture, In Vitro Organogenesis and Regeneration of Plantago lanceolata [PDF]

, 2020
Samaneh Rahamouz-Haghighi, Khadijeh Bagheri, Hossein Danafar, Ali Sharafi   +3 more
openalex   +1 more source

Epidermal Cell Dynamics Regulates Rice Lamina Joint Morphogenesis and Leaf Angle Formation through OsZHD1 and OsZHD2 Regulation

Advanced Science, EarlyView.
The lamina joint determines leaf angle and plant architecture. Xu et al. establish a live‐imaging system for the rice lamina joint and reveal that asymmetric epidermal cell elongation and division between the lateral and medial edges drive leaf angle formation.
Yiru Xu, Heng Zhou, Xiaojiang Wu, Wuyu Cui, Shouling Xu, Xi He, Dan Xiang, Ming Zhou, Xiuqin Rao, Lilan Hong   +9 more
wiley   +1 more source

Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays

Cell, 2021
Ao Chen, Sha Liao, Mengnan Cheng, Kailong Ma, Liang Wu, Yiwei Lai, Xiaojie Qiu, Jin Yang, Wenjia Li, Jiangshan Xu, Shijie Hao, Xin Wang, Huifang Lu, Xi Chen, Xingmin Liu, Xin Huang, Feng Lin, Zhao-Peng Li, Yanping Hong, Defeng Fu, Yujia Jiang, Jian Peng, Shuai Liu, Mengzhe Shen, Chuanyu Liu, Quan-Zhen Li, Yue Yuan, Hui-chao Zheng, Zhifeng Wang, Zhaohui Wang, Haitao Xiang, Lei Han, Baoming Qin, Pengcheng Guo, Pura Muñoz- Cánoves, J. Thiery, Qingfeng Wu, Fuxiang Zhao, Mei Li, Haoyan Kuang, Junhou Hui, Ou Wang, Haorong Lu, Bo Wang, Shiping Liu, Ming Ni, Wenwei Zhang, F. Mu, Ye Yin, Huanming Yang, M. Lisby, R. Cornall, J. Mulder, M. Uhlén, M. Esteban, Yuxiang Li, Longqi Liu, Xun Xu, Jian Wang   +58 more
semanticscholar   +1 more source

Single‐Cell Transcriptomic Atlases of Camels and Cattle Unravel Molecular Evolution of Digestive and Metabolic Systems

Advanced Science, EarlyView.
We generated multi‐tissue single‐cell transcriptomic atlases of camels and cattle, uncovering conserved and lineage‐specific cellular features across digestive and metabolic systems. Cross‐species comparisons revealed the evolutionary origin of the camel glandular sac and identified novel cell populations linked to physiological specialization ...
Tao Shi, Huiquan Shan, Haoping Wang, Xi Guo, Houcheng Li, Bo Han, Senlin Zhu, Fei Wang, Guanghui Tan, Zhannur Niyazbekova, Jilong Ren, Yaqi Zhou, Qi Zhang, Weijie Zheng, Minghui Jia, Ao Zhang, Xuesha Cao, Huizeng Sun, Dongxiao Sun, Lingzhao Fang, Yi Zheng, Xihong Wang, Yu Jiang   +22 more
wiley   +1 more source

A Review of the Risk Factors and Approaches to Prevention of Post-Reperfusion Syndrome During Liver Transplantation

Organogenesis
Post-reperfusion syndrome (PRS) is a severe and highly lethal syndrome that occurs after declamping the portal vein forceps during liver transplantation.
Qian Gao, Jin-Zhen Cai, He Dong
doaj   +1 more source