Results 111 to 120 of about 72,062 (325)
OrganogenesisHepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality globally. HCC is highly heterogenous with diverse etiologies leading to different driver mutations potentiating unique tumor immune microenvironments.
Brandon M. Lehrich, Evan R. Delgado
doaj +1 more source
Nature Communications, 2020 How and where VEGF-C is processed in lymphangiogenesis is unclear. Here, the authors show that development of the zebrafish lymphatic system is locally restricted by Vegfc maturation causing lymphatic sprouting in certain regions, which is regulated by ...
Guangxia Wang +10 more
doaj +1 more source
Simulating Organogenesis: Algorithms for the Image-based Determination of Displacement Fields [PDF]
arXiv, 2014 Recent advances in imaging technology now provide us with 3D images of developing organs. These can be used to extract 3D geometries for simulations of organ development. To solve models on growing domains, the displacement fields between consecutive image frames need to be determined. Here we develop and evaluate different landmark-free algorithms for
arxiv
CRISPR/Cas9 Knockout of Shell Matrix Protein 1 in the Slipper‐Snail Crepidula atrasolea
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.Methods for CRISPR/Cas9 shell matrix protein knockout in the snail, Crepidula atrasolea including optimizing RNP delivery and embryo husbandry, to the use of Sanger and MiSeq sequencing, and high‐content screening of embryos to characterize the loss of Shell Matrix Protein 1 (SMP1) during larval shell development.
Grant Batzel +13 more
wiley +1 more source
The role of pioneer transcription factors in the induction of direct cellular reprogramming
Regenerative Therapy, 2023 Regenerative medicine is a highly advanced medical field that aims to restore tissues and organs lost due to diseases and injury using a person's own cells or those of others.
Kenichi Horisawa, Atsushi Suzuki
doaj
New clues for organogenesis [PDF]
Journal of Molecular Cell Biology, 2012 Organogenesis is a conventional research area in developmental biology. Recent research progresses on stem cell, epigenetics, no-coding RNA and other newpropertiesofmulticellularorganismshavetransformed the organogenesis research as a frontier of life science.
openaire +3 more sources
Molecular Nutrition &Food Research, EarlyView.(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez +5 more
wiley +1 more source
Cell Reports, 2018 Summary: Recent progress in direct lineage reprogramming has enabled the generation of induced hepatocyte-like (iHep) cells and revealed their potential as an alternative to hepatocytes for medical applications.
Junpei Yamamoto +4 more
doaj
Simulating Organogenesis in COMSOL: Tissue Mechanics [PDF]
arXiv, 2017 During growth, tissue expands and deforms. Given its elastic properties, stresses emerge in an expanding and deforming tissue. Cell rearrangements can dissipate these stresses and numerous experiments confirm the viscoelastic properties of tissues [1]-[4].
arxiv
Nano Select, EarlyView.Detection of cancer through the identification of EV markers and CTCs using microfluidic systems is rapidly advancing. These markers are typically identified from liquid biopsy samples, which offer a highly favorable alternative to traditional biopsy methods due to their non‐invasive nature.
Bahareh Valinezhad Saghezi +2 more
wiley +1 more source