Results 21 to 30 of about 366 (120)

Gold(I)‐Catalyzed C(sp3)–C(sp) Cross‐Coupling: Access to Alkynylated Tetrahydrofuran Derivatives

Advanced Synthesis &Catalysis, Volume 368, Issue 11, 3 June 2026.
An Au(I)‐catalyzed C(sp3)–C(sp) cross‐coupling, unsuccessful under photosensitized conditions for vinylgold(I) complexes, is achieved using MeDalPhosAuCl under thermal conditions, giving alkynylated tetrahydrofuran derivatives. The reaction proceeds via an Au(III) intermediate formed by oxidative addition of an alkynyl iodide.
Jorge C. Herrera‐Luna, Wided Hagui, Damien Tocqueville, Eleonora Anelli, Agathe Espagne, Cyril Ollivier, Virginie Mouriès‐Mansuy, Louis Fensterbank   +7 more
wiley   +1 more source

Silyl Rearrangements in Gold‐Catalyzed Transformations

European Journal of Organic Chemistry, Volume 29, Issue 15, 22 April 2026.
The synergy between the exceptional ability of gold catalysts to activate unsaturated substrates and the inherent tendency of organosilicon reagents to undergo silyl‐group rearrangements has unlocked a range of novel transformations, enabling access to otherwise challenging molecular architectures.
Patricia García‐Martínez, Luis A. López   +1 more
wiley   +1 more source

Proteomic analysis of A2780/S ovarian cancer cell response to the cytotoxic organogold(III) compound Aubipyc [PDF]

Journal of Proteomics, 2014
Aubipyc is an organogold(III) compound endowed with encouraging anti-proliferative properties in vitro that is being evaluated pre-clinically as a prospective anticancer agent. A classical proteomic approach is exploited here to elucidate the mechanisms of its biological actions in A2780 human ovarian cancer cells.
GAMBERI, TANIA, MASSAI, LARA, MAGHERINI, FRANCESCA, LANDINI, IDA, FIASCHI, TANIA, SCALETTI, FEDERICA, Gabbiani C, Bianchi L, Bini L, NOBILI, STEFANIA, PERRONE, GABRIELE, MINI, ENRICO, MESSORI, LUIGI, MODESTI, ALESSANDRA   +13 more
openaire   +7 more sources

Coupling Molecular Rotation and Symmetry to Control Solid‐State Chiroptical Properties in Crystalline Chiral N‐Heterocyclic Carbene Au(I) Complexes

Aggregate, Volume 7, Issue 3, March 2026.
Rotational dynamics within chiral NHC–Au(I) molecular crystals are shown to drive symmetry change from C2 to D2‐like arrangements. Solid‐state 2H NMR and computational studies reveal that internal motion modulates molecular symmetry, thereby affecting chiroptical properties such as temperature‐dependent emission and glum.
Pingyu Jiang, Alexander S. Mikherdov, Hajime Ito, Mingoo Jin   +3 more
wiley   +1 more source

Broadening the Workflow for Synchrotron‐Based X‐Ray Fluorescence and X‐Ray Absorption Spectroscopy Imaging of Low‐Abundance Cellular Metals

Chemistry–Methods, Volume 6, Issue 3, March 2026.
We present an accessible plunge‐freezing and freeze‐drying workflow for preparing adherent mammalian cells for synchrotron‐based nanofocused X‐ray fluorescence (XRF) microscopy and X‐ray absorption spectroscopy (XAS), enabling sub‐micron mapping of metal distribution and chemical speciation.
Joaquin Tamargo‐Azpilicueta, Rafael L. Giner‐Arroyo, Pablo Rivero‐García, Sofia Diaz‐Moreno, Miguel A. Gomez‐Gonzalez, Abbey Telfer, Michelangelo Campanella, Miguel A. De la Rosa, Irene Díaz‐Moreno   +8 more
wiley   +1 more source

ADMET Profiling of the Metallodrugs: A Comparative Review of Platinum, Palladium, Gold, Ruthenium, Copper, and Zinc Anticancer Complexes

Bioinorganic Chemistry and Applications, Volume 2026, Issue 1, 2026.
The successful clinical use of metal‐based anticancer agents depends heavily on a detailed understanding of their absorption, distribution, metabolism, excretion, and toxicology (ADMET) profiles. This review evaluates the ADMET properties of anticancer complexes involving platinum, palladium, gold, ruthenium, copper, and zinc.
Meshack Kotonto Tini, John Karanja, Lawrence Odiwuor Omwai, Daniel Onunga, Njogu M. Kimani, Charles O. Ochieng, Chun Xu   +6 more
wiley   +1 more source

Differentiating between F and OH Ligands in Homologous Gold(III) Complexes beyond X‐Ray Crystallography

European Journal of Inorganic Chemistry, Volume 28, Issue 34, December 1, 2025.
A subtle hydrogen‐bonding lock enables the unequivocal structural differentiation between fluoride and hydroxide in the unusual couple of homologous organogold(III) complexes [PPh4][(CF3)3AuF] and [PPh4][(CF3)3Au(OH)] (see adjacent figure). The homologous fluoride and hydroxide complexes of gold(III) [PPh4][(CF3)3AuX] [X = F (1), OH (2)] have been ...
Alberto Pérez‐Bitrián, Daniel Joven‐Sancho, Miguel Baya, Antonio Martín, Jesús Orduna, Babil Menjón   +5 more
wiley   +1 more source

Gold‐Dithiocarbamato Glycoconjugates as Potential Anticancer Agents: Design, Physico‐Chemical Characterization, and In Vitro Biological Activity

ChemBioChem, Volume 26, Issue 22, November 17, 2025.
Metal‐dithiocarbamato glycoconjugates based on gold(III), gold(I)‐phosphino, and gold(I)‐carbene scaffolds are here investigated as potential anticancer agents. Contrary to expectations, they induce cell death by acting at the extracellular level rather than targeting overexpressed glucose transporters.
Andrea Pettenuzzo, Jessica Wölker, Luciano Marchiò, Ingo Ott, Luca Ronconi   +4 more
wiley   +1 more source

Expanding the Chemical Space of Allyl Palladates with Anticancer Properties

European Journal of Inorganic Chemistry, Volume 28, Issue 18, June 24, 2025.
Novel allyl palladates with diverse azolium ligands exhibit strong cytotoxicity against cancer cells, with some surpassing cisplatin. Compounds with thioether or selenoether groups show the best selectivity, making them promising candidates for further study. Allyl palladates are emerging as promising anticancer agents due to their unique mechanisms of
Alessia Schiavo, Giacomo Baio, Francis Bru, Irene Guerra, Victoria Mechrouk, Thierry Achard, Sara Baldissin, Stéphane Bellemin‐Laponnaz, Catherine S. J. Cazin, Cristina Tubaro, Fabiano Visentin, Isabella Caligiuri, Flavio Rizzolio, Steven P. Nolan, Thomas Scattolin   +14 more
wiley   +1 more source

Oxidation State and Halogen Influence on the NHC‐Gold‐Halide‐Catalyzed Cyclization of Propargylic Amides

Advanced Synthesis &Catalysis, Volume 366, Issue 24, Page 5108-5122, December 17, 2024.
Abstract The homogeneously catalyzed cycloisomerization reaction of propargylic amides was tested as benchmark reaction for two homologous series of Au(I) and Au(III) complexes with NHC ligands. This reaction is known to afford either aromatic oxazoles or dihydrooxazoles, depending on the oxidation state of the applied gold catalysts. For this purpose,
Nicola Sargentoni, Rossana Galassi, Lorenzo Luciani, Frank Rominger, Matthias Rudolph, A. Stephen. K. Hashmi   +5 more
wiley   +1 more source