Results 141 to 150 of about 114,312 (393)
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
Organoids and Commercialization
, 2022 Organoids are 3D miniature tissue mimics and have been effectively used for various purposes, including disease modeling, various drug screening, mechanism of pathogenesis, stem cell research, and tumor immunology. Organoids are as varied as the body’s tissues and organs and have enormous economic potential.
Anubhab, Mukherjee, +4 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.A scalable biomimetic platform transforms bioinert poly(ethylene glycol) diacrylate into neuroinstructive matrices via integrating solvent transfer‐induced phase separation, microfluidics, and 3D bioprinting. Bicontinuous, hyperbolically curved microporous networks embedded within a fibrous construct elicit rapid adhesion, robust proliferation, and ...
Prince D. Okoro +8 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Advances in integrating artificial intelligence into 3D bioprinting are systematically reviewed here. Machine learning, computer vision, robotics, natural language processing, and expert systems are examined for their roles in optimizing bioprinting parameters, real‐time monitoring, quality control, and predictive maintenance.
Joao Vitor Silva Robazzi +10 more
wiley +1 more source
Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis. [PDF]
, 2019 The development of the mammalian retina is a complicated process involving the generation of distinct types of neurons from retinal progenitor cells (RPCs) in a spatiotemporal-specific manner.
An, Qin +9 more
core
, 2015 Collective cell responses to exogenous cues depend on cell-cell interactions. In principle, these can result in enhanced sensitivity to weak and noisy stimuli.
Amar, Patrick +11 more
core +3 more sources
Advanced Functional Materials, EarlyView.An innovative fabrication platform for 3D microelectrode arrays (MEAs) is presented, utilizing a 3D printer and the capillary action of electrically conductive inks. This approach enables the simple and versatile fabrication of 3D MEAs with complex structures.
Dongjo Yoon, Yoonkey Nam
wiley +1 more source
Medecine sciences : M/S, 2020 As burden of chronic respiratory diseases is constantly increasing, improving in vitro lung models is essential in order to reproduce as closely as possible the complex pulmonary architecture, responsible for oxygen uptake and carbon dioxide clearance. The study of diseases that affect the respiratory system has benefited from in vitro reconstructions ...
Bourguignon, Chloé +10 more
openaire +2 more sources
Reconfigurable Microenvironments Uncover Mechano‐Sensing Timescales and Direct Cell Polarity
Advanced Functional Materials, EarlyView.A synthetic DNA‐crosslinked cell culture matrix enables control over the mechanical microenvironment surrounding cells. Independent tuning of stiffness and stress relaxation uncovers distinct timescales of mechano‐sensing that regulate cell behavior.
Syuan‐Ku Hsiao +4 more
wiley +1 more source
Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.
Cancer Discovery, 2018 Pancreatic cancer is the most lethal common solid malignancy. Systemic therapies are often ineffective, and predictive biomarkers to guide treatment are urgently needed.
Hervé Tiriac +69 more
semanticscholar +1 more source