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Harnessing organoid technology in urological cancer: advances and applications in urinary system tumors. [PDF]
World J Surg OncolWang X, Lin D, Feng N.
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Nature Reviews Materials, 2021 Organoids are in vitro miniaturized and simplified model systems of organs that have gained enormous interest for modelling tissue development and disease, and for personalized medicine, drug screening and cell therapy. Despite considerable success in culturing physiologically relevant organoids, challenges remain to achieve real-life applications.
Moritz Hofer, Matthias P Lutolf
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Brain organoid reservoir computing for artificial intelligence
Nature Electronics, 2023Hongwei Cai, Zhuhao Wu, Jason Tchieu
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Nature Cancer, 2022 Models that recapitulate the complexity of human tumors are urgently needed to develop more effective cancer therapies. We report a bank of human patient-derived xenografts (PDXs) and matched organoid cultures from tumors that represent the greatest ...
Sandra D Scherer +2 more
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Tissue geometry drives deterministic organoid patterning
Science, 2022 Description Spatial and temporal organoid control Stem cell–derived organoids form through self-organization and serve as models for organ development, function, and disease, with potential applications in drug development and personalized medicine ...
Nikolce Gjorevski +2 more
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iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer
Nature, 2023, Aymeric Silvin
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Decellularized Extracellular Matrix for Remodeling Bioengineering Organoid's Microenvironment.
Small, 2023Over the past decade, stem cell- and tumor-derived organoids are the most promising models in developmental biology and disease modeling, respectively.
Liye Zhu +5 more
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Generation of Organoids and Analysis of Ferroptosis in Organoids
2023Ferroptosis is a unique form of iron-dependent cell death induced by lipid peroxidation and subsequent plasma membrane rupture, which sets it apart from other types of regulated cell death. Ferroptosis has been linked to a diverse range of biological processes, such as aging, immunity, and cancer. Organoids, on the other hand, are three-dimensional (3D)
Wenxin, Li +4 more
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