Results 361 to 370 of about 114,312 (393)

Organoid single-cell genomic atlas uncovers human-specific features of brain development

open access: yesNature, 2019
The human brain has undergone substantial change since humans diverged from chimpanzees and the other great apes1,2. However, the genetic and developmental programs that underlie this divergence are not fully understood.
Zhisong He   +2 more
exaly   +2 more sources
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Recapitulating macro-scale tissue self-organization through organoid bioprinting

Nature Materials, 2020
Jonathan A Brassard   +2 more
exaly   +2 more sources

Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation

open access: yesNature Materials, 2020
Directed differentiation of human pluripotent stem cells to kidney organoids brings the prospect of drug screening, disease modelling and the generation of tissue for renal replacement.
Kynan T Lawlor   +2 more
exaly   +2 more sources

Cryopreservation of Organoids

Cryoletters, 2023
Organoids represent indispensable opportunities for biomedicine, including drug discovery, cancer biology, regenerative and personalised medicine or tissue and organ transplantation. However, the lack of optimised preservation strategies limits the wide use of organoids in research or clinical fields.
O, Rogulska, J, Havelkova, Y, Petrenko
openaire   +2 more sources

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Nature Medicine, 2019
Jose Espejo Valle-Inclan   +2 more
exaly   +2 more sources

Commercialization of Organoids

Trends in Molecular Medicine, 2020
Organoids have been successfully exploited for drug screening, disease modeling, pathogenesis, and regenerative medicine. Herein, we discuss the progress achieved in the commercialization of organoids in the last few years. We further elaborate on the concept of organoid biobank and highlight ethical and regulatory issues surrounding organoid research ...
Aswathi Ashok   +2 more
openaire   +3 more sources

Advances in Microfluidic Technologies in Organoid Research

Advanced Healthcare Materials, 2023
Organoids have emerged as major technological breakthroughs and novel organ models that have revolutionized biomedical research by recapitulating the key structural and functional complexities of their in vivo counterparts.
Haitao Liu   +4 more
semanticscholar   +1 more source

Cancer modeling meets human organoid technology

open access: yesScience, 2019
Organoids are microscopic self-organizing, three-dimensional structures that are grown from stem cells in vitro. They recapitulate many structural and functional aspects of their in vivo counterpart organs.
David A Tuveson, Hans Clevers
exaly   +2 more sources

A 3D Bioprinted Cortical Organoid Platform for Modeling Human Brain Development

Advanced Healthcare Materials
The ability to promote three‐dimensional (3D) self‐organization of induced pluripotent stem cells into complex tissue structures called organoids presents new opportunities for the field of developmental biology.
Melissa A Cadena   +11 more
semanticscholar   +1 more source

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