Results 371 to 380 of about 114,312 (393)
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High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays
Nature Biomedical Engineering, 2020Nathalie Brandenberg +2 more
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Science, 2017
Hans Clevers pioneered lab-built mini-organs that can serve as models of ...
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Hans Clevers pioneered lab-built mini-organs that can serve as models of ...
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Organogenesis in a dish: Modeling development and disease using organoid technologies
Science, 2014Madeline A Lancaster
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Organoids in immunological research
Nature Reviews Immunology, 2019Much of our knowledge regarding the interactions between epithelial tissues and the immune system has been gathered from animal models and co-cultures with cell lines. However, unique features of human cells cannot be modelled in mice, and cell lines are often transformed or genetically immortalized.
Yotam E. Bar-Ephraim +2 more
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Nature Reviews Cancer, 2019
Neal et al. have successfully established patient-derived organoids of tumour epithelia retaining native immune cells, thereby recapitulating tumour microenvironment diversity and enabling immuno-oncology studies.
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Neal et al. have successfully established patient-derived organoids of tumour epithelia retaining native immune cells, thereby recapitulating tumour microenvironment diversity and enabling immuno-oncology studies.
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Nature Reviews Cancer, 2018
The recent advances in in vitro 3D culture technologies, such as organoids, have opened new avenues for the development of novel, more physiological human cancer models. Such preclinical models are essential for more efficient translation of basic cancer research into novel treatment regimens for patients with cancer.
Jarno Drost, Hans Clevers
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The recent advances in in vitro 3D culture technologies, such as organoids, have opened new avenues for the development of novel, more physiological human cancer models. Such preclinical models are essential for more efficient translation of basic cancer research into novel treatment regimens for patients with cancer.
Jarno Drost, Hans Clevers
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Organoid models of gastrointestinal cancers in basic and translational research
Nature Reviews Gastroenterology and Hepatology, 2020Harry Cheuk Hay Lau +2 more
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