Results 11 to 20 of about 1,268 (144)
Organoides: fundamentos, presente y futuro [PDF]
Revista Peruana de Medicina Experimental y Salud Pública, 2022 Los organoides son estructuras miniaturizadas, generadas principalmente a partir de células madre pluripotentes inducidas, que se cultivan en el laboratorio conservando sus características innatas o adquiridas.
José Amiel-Pérez +2 more
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Jornada de Jóvenes Investigadores del I3AMonocapas Derivadas de Organoides Porcinos en Plataformas Estáticas y Dinámicas: Hacia un Modelo Intestinal Biomimético In ...
semanticscholar +2 more sources
Nature Reviews Methods Primers, 2022 Organoids have attracted increasing attention because they are simple tissue-engineered cell-based in vitro models that recapitulate many aspects of the complex structure and function of the corresponding in vivo tissue. They can be dissected and interrogated for fundamental mechanistic studies on development, regeneration, and repair in human tissues.
Zixuan Zhao +13 more
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Review on the Vascularization of Organoids and Organoids-on-a-Chip [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 The use of human cells for the construction of 3D organ models in vitro based on cell self-assembly and engineering design has recently increased in popularity in the field of biological science. Although the organoids are able to simulate the structures and functions of organs
Xingli Zhao +10 more
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Nature Reviews Materials, 2021 Organoids are in vitro miniaturized and simplified model systems of organs that have gained enormous interest for modelling tissue development and disease, and for personalized medicine, drug screening and cell therapy. Despite considerable success in culturing physiologically relevant organoids, challenges remain to achieve real-life applications.
Moritz Hofer, Matthias P. Lutolf
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Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2018 Introdução: Modelos com maior capacidade preditiva e que produzam resultados a custos mais baixos e em prazos menores são necessários para o desenvolvimento de fármacos. Os sistemas microfisiológicos (SMF) que cultivam tecidos humanos em histoarquitetura
Talita Miguel Marin, Eduardo Pagani
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Méthodes alternatives in vitro pour l’étude des interactions hôte-pathogène du poumon
INRAE Productions Animales, 2023 Les maladies respiratoires, qu’elles touchent les animaux et/ou les hommes, ont un impact sanitaire et économique considérable sur notre société. Pouvoir mieux les contrôler, les traiter et les prédire, nécessite de pouvoir les étudier.
Aude REMOT +7 more
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Organoids and Colorectal Cancer [PDF]
Cancers, 2021 Organoids were first established as a three-dimensional cell culture system from mouse small intestine. Subsequent development has made organoids a key system to study many human physiological and pathological processes that affect a variety of tissues and organs. In particular, organoids are becoming very useful tools to dissect colorectal cancer (CRC)
Antonio Barbáchano +6 more
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Organoides: posibles aplicaciones en la Química Medicinal [PDF]
, 2022 Los avances en la biología de células madre y en el desarrollo de cultivos en tres dimensiones han permitido la generación de nuevos modelos celulares denominados organoides. Los organoides son estructuras multicelulares y autoorganizadas que recapitulan
Pagotto, Romina
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