Results 31 to 40 of about 78,167 (269)

Controlling platinum, ruthenium, and osmium reactivity for anticancer drug design [PDF]

, 2009
The main task of the medicinal chemist is to design molecules that interact specifically with derailed or degenerating processes in a diseased organism, translating the available knowledge of pathobiochemical and physiological data into chemically ...
Bruijnincx, Pieter C. A., Sadler, P. J.
core   +1 more source

Application of Graph Theory to the elaboration of personal genomic data for genealogical research [PDF]

PeerJ Computer Science, 2015
In this communication a representation of the links between DNA-relatives based on Graph Theory is applied to the analysis of personal genomic data to obtain genealogical information.
Vincenzo Palleschi, Luca Pagani, Stefano Pagnotta, Giuseppe Amato, Sergio Tofanelli   +4 more
doaj   +2 more sources

Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis [PDF]

, 2013
Platinum complexes related to cisplatin, cis-[PtCl2(NH3)2], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity ...
Bailey H. H., Ballestrero A., Bellamy W. T., Betanzos-Lara S., Bozic I., Bushra Qamar, Carew J. S., Castonguay A., Chan J., Constantini P., Dai Y., Degterev A., Dindo D., Doroshow J. H., Dyke M. W. Van, Fagan V., Finnilä S., Frank J. E., Fu Y., Fu Y., Gaiddon C., Garbutcheon-Singh K. B., Hannon M. J., Hartinger C. G., Hileman E. A., Holbeck S., Huo H., Ian Hands-Portman, Isolda Romero-Canelón, Jessica M. Hearn, Jordan M. A., Jungwirth U., Kelland L., Kerr J. F., Kroemer G., Lazebnik Y. A., Liu Z., Liu Z., Liu Z., Lu J.-J., McKeage M. J., Millar A. W., Monneret C., Nagata S., Park G. Y., Paull K., Perchellet E. M., Peter J. Sadler, Petrelli A., Pittella F., Porteous C. M., Pracharova J., Purewal M., Rai S. S., Rixe O., Saraste A., Shoemaker R. H., Shoemaker R. H., Siddik Z., Sidler D., Tsutsui T., Türk D., Van den Bogert C., Zalacaín M., Zhang Y.-W., Zhe Liu, Zhou D.-F., Zhu Z.   +67 more
core   +1 more source

Peripherally-metallated porphyrins: meso-n1-porphyrinyl-platinum(II) complexes of 5,15-diaryl- and 5,10,15-triarylporphyrins [PDF]

, 2002
Attempted metathesis reactions of peripherally-metallated meso-η1-porphyrinylplatinum(II) complexes such as trans-[PtBr(NiDPP)(PPh3)2] (H2DPP = 5,15-diphenylporphyrin) with organolithium reagents fail due to competitive addition at the porphyrin ring ...
Arnold, Dennis, Edwards, Alice, Hartnell, Regan   +2 more
core   +2 more sources

Combined LCA and Green Metrics Approach for the Sustainability Assessment of an Organic Dye Synthesis on Lab Scale

Frontiers in Chemistry, 2020
New generation photovoltaic devices have attracted much attention in the last decades since they can be efficiently manufactured employing abundant raw materials and with less-energy intensive processes. In this context, the use of powerful environmental
Maria Laura Parisi, Maria Laura Parisi, Maria Laura Parisi, Alessio Dessì, Lorenzo Zani, Simone Maranghi, Simone Maranghi, Sanaz Mohammadpourasl, Sanaz Mohammadpourasl, Sanaz Mohammadpourasl, Massimo Calamante, Massimo Calamante, Alessandro Mordini, Alessandro Mordini, Riccardo Basosi, Riccardo Basosi, Riccardo Basosi, Gianna Reginato, Adalgisa Sinicropi, Adalgisa Sinicropi, Adalgisa Sinicropi   +20 more
doaj   +1 more source

An overview of the biosensing potential of organometallic compounds

Chemical Physics Impact, 2023
Sensing technology is receiving increasing attention and improvements every day, making it a suggested component of personalized healthcare management.
Durga Prasad Mishra, Biswajeet Acharya, Swarnajeet Tripathy, Binapani Barik, Prafulla Kumar Sahu   +4 more
doaj   +1 more source

An organometallic compound which exhibits a DNA topology-dependent one-stranded intercalation mode [PDF]

, 2016
Understanding how small molecules interact with DNA is essential since it underlies a multitude of pathological conditions and therapeutic interventions.
Adhireksan, Aird, Baruah, Brunk, Chen, Chua, Chua, Davey, Liu, Novakova, Ong, Rescifina, Spingler, Wu, Wu, Wu, Zeglis   +16 more
core   +3 more sources

Magnetism and Electronic Correlations in Quasi-One-Dimensional Compounds [PDF]

, 2008
In this contribution on the celebration of the 80th birthday anniversary of Prof. Ricardo Ferreira, we present a brief survey on the magnetism of quasi-one-dimensional compounds.
Coutinho-Filho, M. D., Montenegro-Filho, R. R., Oliveira, M. H., Raposo, E. P., Vitoriano, C.   +4 more
core   +1 more source

Chemical Functionalization of Carbon Nanomaterials: Bridging the Gap between Simple Carriers and Smart (Metal-free) Catalysts

CHIMIA, 2017
The last few years have witnessed a wonderful technological renaissance that boosted the development of carbon-based nanomaterials (CNMs) doped with light heteroelements and featuring hierarchical porous architectures as valuable metal-free ...
Giulia Tuci, Lapo Luconi, Andrea Rossin, Giuliano Giambastiani   +3 more
doaj   +1 more source

Unusual DNA binding modes for metal anticancer complexes [PDF]

, 2009
DNA is believed to be the primary target for many metal-based drugs. For example, platinum-based anticancer drugs can form specific lesions on DNA that induce apoptosis.
Pizarro, Ana M., Sadler, P. J.
core   +1 more source