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Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition

open access: yesToxics, 2023
Organophosphorus compounds (OPs) have applications in agriculture (e.g., pesticides), industry (e.g., flame retardants), and chemical warfare (nerve agents). In high doses or chronic exposure, they can be toxic or lethal.
V. Aroniadou-Anderjaska   +4 more
semanticscholar   +1 more source

Analytical Evaluation of Carbamate and Organophosphate Pesticides in Human and Environmental Matrices: A Review

open access: yesMolecules, 2022
Pesticides are synthetic compounds that may become environmental contaminants through their use and application. The high productivity achieved in the agricultural industry can be credited to the use and application of pesticides by way of pest and ...
Nonkululeko Landy Mdeni   +3 more
semanticscholar   +1 more source

A case report of delayed lower intestinal bleeding after organophosphate poisoning

open access: yesBMC Gastroenterology, 2021
Background Organophosphate poisoning is a serious issue and it results in significant casualties in developing countries. Since agriculture remains an important and necessary sector of human society and organophosphate are commonly used in agriculture ...
Wei Hung, Tsung-Heng Tsai, Jian-Han Chen
doaj   +1 more source

Study of pattern and outcome of acute poisoning cases at tertiary care hospital in North India

open access: yesJournal of Family Medicine and Primary Care, 2023
Introduction: The WHO 2021 data estimate that 2 million lives and 53 million disability-adjusted life-years were lost in 2019 due to exposures to selected chemicals.
Naman Aggarwal   +7 more
doaj   +1 more source

An Overview: Organophosphate Flame Retardants in the Atmosphere

open access: yesAerosol and Air Quality Research, 2022
Organophosphate flame retardants (OPFRs) have been adopted as safer alternatives to polybrominated biphenyl ether flame retardants. However, because of their ubiquitous presence in the environment and the growing evidence of health risks, there has been ...
H. Kung   +4 more
semanticscholar   +1 more source

Poisoning in domestic cats in Brazil: toxicants, clinical signs, and therapeutic approaches [PDF]

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2021
This study evaluated the most common toxic agents affecting domestic cats, the clinical signs of toxicity, and the therapeutic approaches for recovery. A survey on poisoning in cats was conducted among small animal veterinary practitioners from 2017 to ...
M.P.B. Jardim   +3 more
doaj   +1 more source

Association Between PON1 (L55M and Q192R) Genetic Polymorphism and Recurrent Pregnancy Loss in North Indian Women Exposed to Pesticides

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2022
Objective The aim of the present study was to examine the relation between the PON1 polymorphisms and recurrent pregnancy loss (RPL). Methods In a cross-sectional study, blood samples were collected from 100 females.
Shyam Pyari Jaiswar   +5 more
doaj   +1 more source

Geospatial model of organophosphate insecticide residues in shallot land in Wanasari Sub-district, Brebes Regency, Central Java Province, Indonesia [PDF]

open access: yesE3S Web of Conferences, 2020
Organophosphates are a group of chemicals that are still allowed to be used in Indonesia and much preferred by most farmers. Excessive usage of organophosphate is expected to contaminate the soil, water, plants, the environment and humans.
Indratin   +2 more
doaj   +1 more source

Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers

open access: yesEnvironmental Health Perspectives, 2021
Background: To date, the toxicity of organophosphate esters has primarily been studied regarding their use as pesticides and their effects on the neurotransmitter acetylcholinesterase (AChE).
H. Patisaul   +10 more
semanticscholar   +1 more source

Effectiveness of Fresh Frozen Plasma in Management of Acute Organophosphate Intoxicated Patients: An Updated Systematic Review and Meta-Analysis [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2019
Background:Organophosphate (OP) poisoning is still a major health concern in both developed and developing countries. The standard treatment approaches of (OP) poisoning are not always available as well so they may show a limited success rate.
Ola Nafea   +4 more
doaj   +1 more source

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