Results 71 to 80 of about 15,797 (250)

Wild Honey Intoxication: A Case Series From Nepal

Clinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Wild honey poisoning can cause serious cardiovascular complications, including bradycardia and hypotension, even with small amounts (1–2 teaspoons) consumed. Symptoms typically emerge within 30–45 min of ingestion. Early intervention with IV fluids and atropine is effective in most cases, but severe cases may require vasopressors, particularly
Rukma Raj Kafle, Rakshya Arun Kandel, Sabin Chaulagain, Angela Basnet, Shiva Kumar Ojha, Alok Atreya   +5 more
wiley   +1 more source

Acute cypermethrin and other pyrethroid poisoning – An organophosphate-like poisoning: A case report and review

Toxicology Reports, 2023
Background: South Africa is one of the largest importers of pesticides in Africa. Pesticides play an integral role in food security and ensuring economic survival.
Leon Daniel Scheepers, Robert Freercks, Elizabeth van der Merwe   +2 more
doaj  

Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification. [PDF]

, 2014
Intoxication by organophosphate (OP) nerve agents and pesticides should be addressed by efficient, quickly deployable countermeasures such as antidotes reactivating acetylcholinesterase or scavenging the parent OP.
Amitai, Gabriel, Fokin, Valery V, Radić, Zoran, Sharpless, K Barry, Sit, Rakesh K, Taylor, Palmer   +5 more
core  

Opsoclonus‐Myoclonus: Not Always Paraneoplastic

Movement Disorders Clinical Practice, EarlyView.
Fernanda Lustosa Cabral Gomez, Luiz José Malta Gaia Ferreira Júnior, Sofia Mônaco Gama, Fabiano Moulin de Moraes, Flávio Moura Rezende Filho   +4 more
wiley   +1 more source

A Critical Overview of Common Foodborne Toxicants and Methods for Their Reliable Detection

Food Frontiers, Volume 6, Issue 4, Page 1658-1700, July 2025.
ABSTRACT Food is an essential commodity for human health. However, toxicants such as mycotoxins, heavy metals, acrylamide, and pesticides can be present in food either naturally or through processing, packaging, or some anthropogenic activities. A thorough review of carefully selected studies revealed that climate change and pandemics have led to an ...
Betty Bowe Acquah, John‐Lewis Zinia Zaukuu   +1 more
wiley   +1 more source

Avaliação da gravidade de doentes ventilados numa unidade de cuidados intensivos respiratórios pelo sistema APACHE II.

Acta Médica Portuguesa, 1992
APACHE II system, is a simple and inexpensive method to evaluate severity of Intensive Care Patients. In a 2 years period (between 1988 and 1990), grading severity using APACHE II system, was performed on 498 consecutive mechanical Ventilated Patients in
G Brum, E Teixeira, C Barroso, F Monteiro, S Alves, V Magalhães, M Bastardo, A Couto, M F Freitas e Costa   +8 more
doaj   +1 more source

Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme [PDF]

, 2010
Organophosphorus (OP) nerve agents are potent suicide inhibitors of the essential neurotransmitter-regulating enzyme acetylcholinesterase. Due to their acute toxicity, there is significant interest in developing effective countermeasures to OP ...
Andrew C. Hemmert, C. Linn Cadieux, Carol C. Edwards, Douglas M. Cerasoli, Fernando Rodrigues-Lima, John R. Cashman, Jonathan S. Edwards, Lyudmila Tsurkan, Matthew R. Redinbo, Monika Wierdl, Philip M. Potter, Roberto A. Chica, Shane A. Kasten, Stephen L. Mayo, Steven M. Lewis, Tamara C. Otto   +15 more
core   +6 more sources

Epidemiology of Poisoning Cases at Lumbini Medical College, Nepal: A 5‐Year Retrospective Study

Health Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background and Aims Poisoning is a major global public health problem, disproportionately burdensome in low‐resource healthcare settings. The objective of this study was to gain epidemiological insights into poisoning cases at Lumbini Medical College and Teaching Hospital over a period of 5 years.
Samata Nepal, Alok Atreya, Prakriti Regmi, Prasun Shrestha, Rishav Babu Shrestha, Laxmi Prasad Sapkota, Ritesh G. Menezes, Himal Ghimire, Suraj Dhakal, Shikha Pahari   +9 more
wiley   +1 more source

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

Medicinal Research Reviews, Volume 45, Issue 4, Page 1251-1274, July 2025.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni, Giulia Galli, Clelia Dallanoce, Marco De Amici, Pau Gorostiza, Carlo Matera   +5 more
wiley   +1 more source

Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
Cyanide is coined “the classic metabolic poison”; however, FDA‐approved cyanide chelators do not counteract cyanide's metabolic damage. Here, we review the mechanisms of cyanide toxicity, with a focus on intermediary metabolism. We present the theory that, within the innate plasticity of the metabolome, there may reside metabolic pathways that can ...
Vik S. Bebarta, Anjali K. Nath
wiley   +1 more source