Results 21 to 30 of about 9,971 (194)

Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme [PDF]

, 2010
Organophosphorus (OP) nerve agents are potent suicide inhibitors of the essential neurotransmitter-regulating enzyme acetylcholinesterase. Due to their acute toxicity, there is significant interest in developing effective countermeasures to OP ...
Andrew C. Hemmert, C. Linn Cadieux, Carol C. Edwards, Douglas M. Cerasoli, Fernando Rodrigues-Lima, John R. Cashman, Jonathan S. Edwards, Lyudmila Tsurkan, Matthew R. Redinbo, Monika Wierdl, Philip M. Potter, Roberto A. Chica, Shane A. Kasten, Stephen L. Mayo, Steven M. Lewis, Tamara C. Otto   +15 more
core   +6 more sources

A study of profile of patients with organophosphorus compound poisoning at a teaching hospital

MRIMS Journal of Health Sciences, 2014
Background: Organophosphorus compound poisoning forms an important public health problem especially in developing countries and rural population. Apart from its agricultural benefit its increasing use in agriculture, the farmer's and those involved in ...
Vinod Govsavi, Vinayak E Shegokar, Sandeep M Bhelkar, Sudhir Tungikar   +3 more
doaj   +1 more source

Zebrafish models for human acute organophosphorus poisoning [PDF]

, 2015
Terrorist use of organophosphorus-based nerve agents and toxic industrial chemicals against civilian populations constitutes a real threat, as demonstrated by the terrorist attacks in Japan in the 1990 s or, even more recently, in the Syrian civil war ...
Arick II, Mark, Arick II, Mark, Babin, Patrick J., Cachot, Jérôme, Escalon, B. Lynn, Faria, Melissa, Garcia-Reyero, Natàlia, Knoll-Gellida, Anja, Le Bihanic, Florane, Le Bihanic, Florane, Mathieu, Guilaine, Padrós, Francesc, Prats, Eva, Raldúa, Demetrio, Rial, Eduardo, Sebastián, David, Soares, Amadeu M. V. M., Zorzano, Antonio   +17 more
core   +4 more sources

Biochemical indicators and the Peradeniya Organophosphate Poisoning scale in prediction and prognosis of organophosphorus poisoning: An observational prospective study

Journal of Acute Disease, 2023
Objective: To study the value of some biochemical indicators and Peradeniya Organophosphate Poisoning scale in prediction and prognosis of organophosphorus poisoning. Methods: This was a hospital-based prospective, observational study.
Shivcharan Jelia, Banwari Lal, Divya Airan   +2 more
doaj   +1 more source

Predicting outcome using butyrylcholinesterase activity in organophosphorus pesticide self-poisoning [PDF]

, 2008
Background: The usefulness of a low butyrylcholinesterase (BuChE) activity on admission for predicting severity in acute organophosphorus (OP) insecticide poisoning has long been debated. Previous studies have been confounded by the inclusion of multiple
Buckley, N. A., Eddleston, M., Eyer, P., Sheriff, M. H. Rezvi, Worek, F.   +4 more
core   +1 more source

Black Coloured Urine following Organophosphorus Poisoning: Report of Two Cases

Case Reports in Critical Care, 2014
Organophosphorus poisoning is common in rural Asia. Clinical features result from overactivity of acetylcholine receptors. Blackish discoloration of urine is not a feature of organophosphorus poisoning.
Aneesh Basheer, Sudhagar Mookkappan, Vijay Shanmugham, Nagarajan Natarajan, Kiran Kulirankal   +4 more
doaj   +1 more source

A profile of acute poisonings: A retrospective study

Journal of the Scientific Society, 2015
Background and Objective: Intentional self-poisoning is a major problem in developing countries. Thus, the main objective of this study was to characterize the poisoning cases and related mortality among patients admitted with poisoning in a tertiary ...
Thalappillil Mathew Celine, Jimmy Antony
doaj   +1 more source

NEW PHOSPHORUS COMPOUNDS K[PCL3(X)] (X= SCN, CN): PREPARATION AND DFT AND SPECTROSCOPIC STUDIES [PDF]

, 2016
Indexación: Web of Science. Scielo.Two new phosphorus complexes, potassium trichlorothiocyanophosphate (III) (PTCTCP; K[PCl3(SCN)]) and potassium trichlorocyanophosphate (III) (PTCCP; K[PCl3(CN)]) were synthesized from the reaction of KSCN and KCN ...
GERLI–CANDIA, LORENA, GHAMAMI, SHAHRIAR, LASHGARI, AMIR, RAMIREZ-TAGLE, RODRIGO, SALGADO-MORAN, GUILLERMO   +4 more
core   +3 more sources

Outcome prediction using sequential organ failure assessment (SOFA) score and serum lactate levels in organophosphate poisoning

Journal of Family Medicine and Primary Care, 2023
Background: Organophosphorus compounds are widely used as pesticides in agriculture practicing countries like India. Since it is readily available and accessible, it is one of the most commonly used agents for suicidal poisoning.
Govinda Balmuchu, Manoj K. Mohanty, Manas R. Sahu, Upendra Hansda, Alagarasan Naveen, Preetam K. Lenka   +5 more
doaj   +1 more source

Metabolism of profenofos to 4-bromo-2-chlorophenol, a specific and sensitive exposure biomarker. [PDF]

, 2013
Profenofos is a direct acting phosphorothioate organophosphorus (OP) pesticide capable of inhibiting β-esterases such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase.
Chi, Lai-Har, Dadson, Oswald A, Ellison, Corie A, Farahat, Fayssal M, Farahat, Taghreed, Lein, Pamela J, McGarrigle, Barbara P, Olson, James R, Singleton, Steven T   +8 more
core   +1 more source