Results 161 to 170 of about 3,507 (204)
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Chemoprevention of cancer by organoselenium compounds
Journal of Cellular Biochemistry, 1995A major research goal of our laboratories is the development of new organoselenium cancer chemopreventive agents with less toxicity compared to some of the historical selenium compounds, such as sodium selenite. Ideally, such agents would be employed to inhibit tumor development in different organs caused by a variety of chemical carcinogens ...
Karam El-Bayoumy +2 more
exaly +3 more sources
Organoselenium Compounds in Medicinal Chemistry
ChemMedChemAbstractThe chemical and biological interest in this element and the molecules bearing selenium has been exponentially growing over the years. Selenium, formerly designated as a toxin, becomes a vital trace element for life that appears as selenocysteine and its dimeric form, selenocystine, in the active sites of selenoproteins, which catalyze a wide ...
Juan B Rodríguez +1 more
exaly +4 more sources
Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology
Chemical Reviews, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
Cristina W Nogueira +2 more
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Organoselenium compounds as fluorescent probes
Coordination Chemistry Reviews, 2015Abstract Fluoroprobes are compounds which detect analytes (neutral molecules and ions) by simple, inexpensive, and fast fluorimetric responses. In this review, we provide insights into the development of new organoselenium compounds as fluoroprobes for detecting various analytes. These organoselenium fluoroprobes are capable of metal cation and anion
Snigdha Panda +2 more
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Polymers, 2022 The one-pot multicomponent synthetic strategy of organoselenium compounds represents an alternative and robust protocol to the conventional multistep methods. During the last decade, a potential advance has been made in this domain. This review discusses
Saad Shaaban +2 more
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Synthesis and in Silico Investigation of Organoselenium-Clubbed Schiff Bases as Potential Mpro Inhibitors for the SARS-CoV-2 Replication [PDF]
Life, 2023 Since the first report of the organoselenium compound, ebselen, as a potent inhibitor of the SARS-CoV-2 Mpro main protease by Z. Jin et al. (Nature, 2020), different OSe analogs have been developed and evaluated for their anti-COVID-19 activities. Herein,
Saad Shaaban +2 more
exaly +2 more sources
Recent Advances in Organoselenium Catalysis
Current Organic Synthesis, 2022Abstract: : Organoselenium chemistry has developed as an important tool in the field of synthetic and medicinal chemistry. Various organoselenium reagents have been developed and used successfully to achieve different organic transformations such as the selenocyclizations, oxyselenenylations and selenoxide eliminations etc. Additionally, the potential
Santosh G. +2 more
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Organoselenium ligands in catalysis
Dalton Transactions, 2012Organoselenium ligands are building blocks of several transition metal complexes which catalyze various organic reactions efficiently in solution. In this review the survey of developments pertaining to the designing of such complexes (along with their Se-ligands), and their uses as catalysts for various organic reactions has been presented with ...
Arun, Kumar +3 more
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The Nature of the Interaction of Organoselenium Molecules with Diiodine
The Journal of Physical Chemistry A, 2011The electronic structure of charge-transfer complexes of organoselenium compounds with diiodine has been studied at several levels of theory (Hartree-Fock, second order Møller-Plesset, and density functional theory). The complexation energies, optimized geometries, and the topology of the electron density and its Laplacian distribution, including ...
Madzhidov T. +2 more
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Organoselenium Compounds in Cancer Chemoprevention
Mini-Reviews in Medicinal Chemistry, 2008Selenium is an important trace element involved in different physiological functions of human body. Knowledge of selenium in biology of cancer has increased at rapid rate especially during last two decades. Basic research and clinical studies involving animal models and more recently studies in human strongly support the protective role of selenium ...
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