Organoselenium Compounds Derived from Natural Metabolites [PDF]
PharmaceuticalsBackground/Objectives: Natural metabolites, due to their abundance, structural diversity, and availability in enantiomerically pure form, are broadly utilized in the synthesis of reagents, catalysts, building blocks, and potential therapeutics.
Agata J. Pacuła-Miszewska +2 more
doaj +5 more sources
Asymmetric Synthesis and Applications of Chiral Organoselenium Compounds: A Review [PDF]
MoleculesThe synthesis and application of organoselenium compounds have developed rapidly, and chiral organoselenium compounds have become an important intermediate in the field of medicine, materials, organic synthesis. The strategy of developing a green economy
Yanyu Jian +3 more
doaj +5 more sources
Mechanochemical synthesis of organoselenium compounds [PDF]
Nature CommunicationsWe disclose herein a strategy for the rapid synthesis of versatile organoselenium compounds under mild conditions. In this work, magnesium-based selenium nucleophiles are formed in situ from easily available organic halides, magnesium metal, and ...
Shanshan Chen +10 more
doaj +5 more sources
Synthesis and Antioxidant Properties of Organoselenium Compounds [PDF]
Current Medicinal Chemistry, 2023 The chemistry of organoselenium reagents provides an asset for organic synthesis. The versatility of these reagents as electrophiles and nucleophiles makes them one of the key components of organic synthesis.
Marina Kostic, Fateh V Singh
exaly +5 more sources
Genotoxicity and cytotoxicity potential of organoselenium compounds in human leukocytes in vitro [PDF]
Saudi Pharmaceutical Journal, 2023 In the current work, cytotoxicity and genotoxicity of different organoselenium compounds were examined using Trypan blue exclusion and alkaline comet assays with silver staining respectively.
Mohammad Ibrahim +9 more
doaj +3 more sources
Progress in the Synthesis of Organoselenium Compounds: Conventional Routes Versus Green Approaches [PDF]
MoleculesOrganoselenium chemistry has progressed from the early synthesis of simple selenoorganic molecules in the 20th century to advanced methodologies aligned with the principles of green chemistry.
Chintankumar Padariya, Anita Kornicka
doaj +3 more sources
The Effect of Organoselenium Compounds on Histone Deacetylase Inhibition and Their Potential for Cancer Therapy [PDF]
International Journal of Molecular Sciences, 2021 Genetic and epigenetic changes alter gene expression, contributing to cancer. Epigenetic changes in cancer arise from alterations in DNA and histone modifications that lead to tumour suppressor gene silencing and the activation of oncogenes.
Ashmika Foolchand +2 more
exaly +3 more sources
Developments in Synthetic Application of Selenium(IV) Oxide and Organoselenium Compounds as Oxygen Donors and Oxygen-Transfer Agents [PDF]
Molecules, 2015 A variety of selenium compounds were proven to be useful reagents and catalysts for organic synthesis over the past several decades. The most interesting aspect, which emerged in recent years, concerns application of hydroperoxide/selenium(IV) oxide and ...
Jacek Młochowski +1 more
doaj +3 more sources
Towards Volatile Organoselenium Compounds with Cost-Effective Synthesis [PDF]
Molecules, 2020 The current portfolio of organoselenium compounds applicable as volatile precursors for atomic layer deposition can be denoted as very limited. Hence, we report herein facile and cost-effective preparation of two bis(trialkylstannyl)selenides as well as ...
Jaroslav Charvot +4 more
doaj +2 more sources
In Silico Investigation on the Binding of Organoselenium Compounds with Target Proteins of SARS-CoV-2 Infection Cycle [PDF]
, 2020 Since the outbreak of coronavirus disease 2019 (COVID-19), researchers have been investigating the potential of several low molecular weight compounds from both natural and synthetic origins to design anti-viral drugs against SARS-CoV-2. On similar lines,
Singh BG, Kunwar A.
europepmc +2 more sources