Results 1 to 10 of about 2,112 (140)
Organoselenium Compounds Derived from Natural Metabolites [PDF]
PharmaceuticalsBackground/Objectives: Natural metabolites, due to their abundance, structural diversity, and availability in enantiomerically pure form, are broadly utilized in the synthesis of reagents, catalysts, building blocks, and potential therapeutics.
Agata J. Pacuła-Miszewska +2 more
doaj +4 more sources
Mechanochemical synthesis of organoselenium compounds [PDF]
Nature CommunicationsWe disclose herein a strategy for the rapid synthesis of versatile organoselenium compounds under mild conditions. In this work, magnesium-based selenium nucleophiles are formed in situ from easily available organic halides, magnesium metal, and ...
Shanshan Chen +10 more
doaj +4 more sources
Asymmetric Synthesis and Applications of Chiral Organoselenium Compounds: A Review [PDF]
MoleculesThe synthesis and application of organoselenium compounds have developed rapidly, and chiral organoselenium compounds have become an important intermediate in the field of medicine, materials, organic synthesis. The strategy of developing a green economy
Yanyu Jian +3 more
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Organoselenium compounds beyond antioxidants. [PDF]
Future Med ChemOrganoselenium chemistry has become a significant field due to its role in synthesizing numerous biologically active and therapeutic compounds. In early phase, researchers focused on designing organoselenium compounds with antioxidant properties and were quite successful.
Mamgain R, Mishra G, Kriti S, Singh FV.
europepmc +5 more sources
Aminic Organoselenium Compounds: Promising Antioxidant Agents [PDF]
ACS OmegaSignificant research interest has been devoted to organoselenium compounds due to their diverse biological activities, particularly their antioxidant properties, which mimic those of glutathione peroxidase (GPx) enzymes. While previous reviews have explored the broad spectrum of organoselenium chemistry and their applications, this review focuses ...
Babli Chhillar +6 more
doaj +5 more sources
Genotoxicity and cytotoxicity potential of organoselenium compounds in human leukocytes in vitro [PDF]
Saudi Pharmaceutical Journal, 2023 In the current work, cytotoxicity and genotoxicity of different organoselenium compounds were examined using Trypan blue exclusion and alkaline comet assays with silver staining respectively.
Mohammad Ibrahim +9 more
doaj +2 more sources
Towards Volatile Organoselenium Compounds with Cost-Effective Synthesis [PDF]
Molecules, 2020 The current portfolio of organoselenium compounds applicable as volatile precursors for atomic layer deposition can be denoted as very limited. Hence, we report herein facile and cost-effective preparation of two bis(trialkylstannyl)selenides as well as ...
Jaroslav Charvot +4 more
doaj +2 more sources
Toxicology and pharmacology of synthetic organoselenium compounds: an update. [PDF]
Arch Toxicol, 2021 Here, we addressed the pharmacology and toxicology of synthetic organoselenium compounds and some naturally occurring organoselenium amino acids. The use of selenium as a tool in organic synthesis and as a pharmacological agent goes back to the middle of the nineteenth and the beginning of the twentieth centuries.
Nogueira CW, Barbosa NV, Rocha JBT.
europepmc +4 more sources
Synthesis and Antioxidant Properties of Organoselenium Compounds
Current Medicinal Chemistry, 2023 Background: The chemistry of organoselenium reagents provides an asset for organic synthesis. The versatility of these reagents as electrophiles and nucleophiles makes them one of the key components of organic synthesis. Various synthetic transformations such as oxyselenenylations, selenocyclization and selenoxide elimination have been successfully ...
Marina D Kostic, Fateh V Singh
exaly +4 more sources
Developments in Synthetic Application of Selenium(IV) Oxide and Organoselenium Compounds as Oxygen Donors and Oxygen-Transfer Agents [PDF]
Molecules, 2015 A variety of selenium compounds were proven to be useful reagents and catalysts for organic synthesis over the past several decades. The most interesting aspect, which emerged in recent years, concerns application of hydroperoxide/selenium(IV) oxide and ...
Jacek Młochowski +1 more
doaj +2 more sources