Results 41 to 50 of about 2,820 (183)

Antimicrobial Coatings for Medical Textiles via Reactive Organo-Selenium Compounds

Molecules, 2023
Bleached and cationized cotton fabrics were chemically modified with reactive organoselenium compounds through the nucleophilic aromatic substitution (SNAr) reaction, which allowed for organo-selenium attachment onto the surface of cotton fabrics via ...
Ejajul Hoque, Phat Tran, Unique Jacobo, Nicholas Bergfeld, Sanjit Acharya, Julia L. Shamshina, Ted W. Reid, Noureddine Abidi   +7 more
doaj   +1 more source

In Vitro Activity of Ebselen and Diphenyl Diselenide Alone and in Combination with Drugs against Trichophyton mentagrophytes Strains

Pharmaceutics, 2022
Background: Dermatophytoses are one of the most prevalent infectious diseases in the world for which the pace of developing new drugs has not kept pace with the observed therapeutic problems.
Sebastian Gnat, Dominik Łagowski, Mariusz Dyląg, Grzegorz Jóźwiak, Aleksandra Trościańczyk, Aneta Nowakiewicz   +5 more
doaj   +1 more source

Reduction of Diphenyl Diselenide and Analogs by Mammalian Thioredoxin Reductase Is Independent of Their Gluthathione Peroxidase-Like Activity: A Possible Novel Pathway for Their Antioxidant Activity

Molecules, 2010
Since the successful use of the organoselenium drug ebselen in clinical trials for the treatment of neuropathological conditions associated with oxidative stress, there have been concerted efforts geared towards understanding the precise mechanism of ...
João Batista Teixeira Rocha, Diego Alves, Lisiane Oliveira Porciúncula, Jéssie Haigert Sudati, Caroline Wagner, Andressa Sausen de Freitas, Alessandro de Souza Prestes, Ige Joseph Kade   +7 more
doaj   +1 more source

Stereoselective Synthesis of Selenium-Containing Glycoconjugates via the Mitsunobu Reaction

Molecules, 2021
A simple and efficient route for the synthesis of new glycoconjugates has been developed. The approach acts as a model for a mini-library of compounds with a deoxy-selenosugar core joined to a polyphenolic moiety with well-known antioxidant properties ...
Luigia Serpico, Mauro De Nisco, Flavio Cermola, Michele Manfra, Silvana Pedatella   +4 more
doaj   +1 more source

Green solvents in organoselenium chemistry [PDF]

, 2019
© 2018, Springer Nature Switzerland AG. Organoselenium chemistry involves unique methods for the preparation of reaction intermediates and biologically relevant compounds.
Divac, Vera, Kostic, Marina
core   +1 more source

Synthesis, antioxidant and anti-microbial properties of two organoselenium compounds [PDF]

, 2015
The aim of this study is synthesis of two different series of organoselenium compounds and available in vitro antioxidant and antimicrobial properties of thee synthetic compounds. The synthetic compounds were identified by H-1-NMR (300 MHz), C-13-NMR (75.
Talas, Zeliha Selamoglu, Ozdemir, Ilknur, Yilmaz, Ismet, Gunal, Selami, Gok, Yetkin, Ates, Burhan   +5 more
core   +2 more sources

Chemoselective Preparation of New Families of Phenolic-Organoselenium Hybrids—A Biological Assessment

Molecules, 2022
Being aware of the enormous biological potential of organoselenium and polyphenolic compounds, we have accomplished the preparation of novel hybrids, combining both pharmacophores in order to obtain new antioxidant and antiproliferative agents.
Paloma Begines, Sergio Martos, Irene Lagunes, Inés Maya, José M. Padrón, Óscar López, José G. Fernández-Bolaños   +6 more
doaj   +1 more source

Organoselenium Compounds: Chemistry and Applications in Organic Synthesis

Chemistry – A European Journal, 2023
AbstractSelenium, originally described as a toxin, turns out to be a crucial trace element for life that appears as selenocysteine and its dimer, selenocystine. From the point of view of drug developments, selenium‐containing drugs are isosteres of sulfur and oxygen with the advantage that the presence of the selenium atom confers antioxidant ...
Juan M. Sonego, Sheila I. de Diego, Sergio H. Szajnman, Carola Gallo‐Rodriguez, Juan B. Rodriguez   +4 more
openaire   +3 more sources

Chemical Kinetics of 2‐, 4‐, and 2,4‐Seleno‐Uracils at Low Temperatures: Tautomerizations and Rotamerizations on Inert Matrices

International Journal of Chemical Kinetics, EarlyView.
ABSTRACT In the interstellar medium, chemical reactions proceed under conditions vastly different to those on Earth; these include extremely low temperatures and densities and take place in the gas phase and on water–ice grains. Understanding the energetics and more importantly the kinetics of such reactions is of relevance to the consequences on how ...
Judith Wurmel, John M. Simmie
wiley   +1 more source

Synthesis and X-ray structures of new phosphorus-selenium heterocycles with an E-P(Se)-E ' (E, E ' = N, S, Se) linkage

, 2010
This work is funded by the EPSRC UKRefluxing a toluene solution of Woollins' reagent, WR, with difunctional aromatic substrates (aryldiamines and aryldithiols) leads to a series of novel five-to seven-membered heterocycles 2a-e, 4a, 4b and 6a-c with an E-
Fuller, Amy L., Woollins, J. Derek, Li, Yang, Hua, Guoxiong, Slawin, Alexandra M. Z.   +4 more
core   +1 more source