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Organoselenium Compounds Derived from Natural Metabolites [PDF]

open access: yesPharmaceuticals
Background/Objectives: Natural metabolites, due to their abundance, structural diversity, and availability in enantiomerically pure form, are broadly utilized in the synthesis of reagents, catalysts, building blocks, and potential therapeutics.
Agata J. Pacuła-Miszewska   +2 more
doaj   +2 more sources

Asymmetric Synthesis and Applications of Chiral Organoselenium Compounds: A Review [PDF]

open access: yesMolecules
The synthesis and application of organoselenium compounds have developed rapidly, and chiral organoselenium compounds have become an important intermediate in the field of medicine, materials, organic synthesis. The strategy of developing a green economy
Yanyu Jian   +3 more
doaj   +2 more sources

Lactiplantibacillus plantarum S1 as a Novel Dual-Functional Probiotic Strain for High-Efficiency Organoselenium Biotransformation in Functional Food Development [PDF]

open access: yesFoods
The microbial conversion of inorganic Se into bioactive organoselenium compounds represents a cutting-edge strategy for developing functional foods with enhanced nutritional value.
Lin Yuan   +5 more
doaj   +2 more sources

Organosulfur and Organoselenium Chemistry [PDF]

open access: yesMolecules
Organosulfur- and organoselenium-containing compounds play a crucial role in organic synthesis [...]
Ming Wang
doaj   +2 more sources

Mechanochemical synthesis of organoselenium compounds [PDF]

open access: yesNature Communications
We disclose herein a strategy for the rapid synthesis of versatile organoselenium compounds under mild conditions. In this work, magnesium-based selenium nucleophiles are formed in situ from easily available organic halides, magnesium metal, and ...
Shanshan Chen   +10 more
doaj   +2 more sources

Synthesis and in Silico Investigation of Organoselenium-Clubbed Schiff Bases as Potential Mpro Inhibitors for the SARS-CoV-2 Replication

open access: yesLife, 2023
Since the first report of the organoselenium compound, ebselen, as a potent inhibitor of the SARS-CoV-2 Mpro main protease by Z. Jin et al. (Nature, 2020), different OSe analogs have been developed and evaluated for their anti-COVID-19 activities. Herein,
Saad Shaaban   +7 more
doaj   +1 more source

Photocatalytic treatment of organoselenium in synthetic mine-impacted effluents

open access: yesWater Science and Technology, 2023
Biological selenium reduction processes are commonly employed as the best available technology (BAT) for selenium removal; however, as a by-product they produce trace amounts of organoselenium compounds with orders of magnitude greater bioaccumulation ...
Jeffrey Thomas Martin   +4 more
doaj   +1 more source

Recent Advances in the Use of Diorganyl Diselenides as Versatile Catalysts

open access: yesMolecules, 2023
The importance of organoselenium compounds has been increasing in synthetic chemistry. These reagents are well-known as electrophiles and nucleophiles in many organic transformations, and in recent years, their functionality as catalysts has also been ...
Gabriel Pereira da Costa   +3 more
doaj   +1 more source

Selenium-Containing Polysaccharides—Structural Diversity, Biosynthesis, Chemical Modifications and Biological Activity

open access: yesApplied Sciences, 2021
Selenosugars are a group of sugar derivatives of great structural diversity (e.g., molar masses, selenium oxidation state, and selenium binding), obtained as a result of biosynthesis, chemical modification of natural compounds, or chemical synthesis ...
Sandra Górska   +2 more
doaj   +1 more source

Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives

open access: yesNature Communications, 2021
Ebselen is an organoselenium drug that inhibits the SARS-CoV-2 main protease (Mpro). Here, the authors co-crystallised Mpro with ebselen and an ebselen derivative and observed an enzyme bound organoselenium covalent adduct in the crystal structures ...
Kangsa Amporndanai   +11 more
doaj   +1 more source

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