Results 11 to 20 of about 3,507 (204)
Genotoxicity and cytotoxicity potential of organoselenium compounds in human leukocytes in vitro
Saudi Pharmaceutical Journal, 2023 In the current work, cytotoxicity and genotoxicity of different organoselenium compounds were examined using Trypan blue exclusion and alkaline comet assays with silver staining respectively.
Mohammad Ibrahim +9 more
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Organoselenium chemistry [PDF]
, 2018 Organoselenium chemistry has been established as a valuable research area in synthetic and medicinal chemistry. After the discovery of the selenoxide elimination reaction in the early 1970s, organoselenium reagents achieved great success in organic synthesis including asymmetric synthesis. More commonly, synthetic transformations such as selenenylation,
Wirth, Thomas
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Modular Generation of Alkyl Selenyl Radicals for the Synthesis of Alkyl Selenides via a Mechanochemical Approach. [PDF]
Adv Sci (Weinh)We present a mechanochemical, radical‐mediated hydroselenation of alkenes under ambient conditions. This method modularly generates alkyl selenyl radicals from elemental selenium and alkyl (pseudo)halides, utilizing PhSiH3 and H2O as hydrogen atom donors, with the water likely originating from the air and/or trace water present in the reagents ...
He X +8 more
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Recent Advances in the Use of Diorganyl Diselenides as Versatile Catalysts
Molecules, 2023 The importance of organoselenium compounds has been increasing in synthetic chemistry. These reagents are well-known as electrophiles and nucleophiles in many organic transformations, and in recent years, their functionality as catalysts has also been ...
Gabriel Pereira da Costa +3 more
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Applied Sciences, 2021 Selenosugars are a group of sugar derivatives of great structural diversity (e.g., molar masses, selenium oxidation state, and selenium binding), obtained as a result of biosynthesis, chemical modification of natural compounds, or chemical synthesis ...
Sandra Górska +2 more
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Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives
Nature Communications, 2021 Ebselen is an organoselenium drug that inhibits the SARS-CoV-2 main protease (Mpro). Here, the authors co-crystallised Mpro with ebselen and an ebselen derivative and observed an enzyme bound organoselenium covalent adduct in the crystal structures ...
Kangsa Amporndanai +11 more
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Organoselenium Chemistry [PDF]
, 2000 Preface ELECTROPHILIC SELENIUM General Introduction Addition Reactions to Double Bonds Selenocyclizations NUCLEOPHILIC SELENIUM Introduction Properties of Selenols and Selenolates Inorganic Nucleophilic Selenium Reagents Organic Nucleophilic Selenium Reagents SELENIUM COMPOUNDS IN RADICAL REACTIONS Homolytic Substitution at Selenium to Generate Radical
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Frontiers in Chemistry, 2022 Reduction of 4,4′-diselanediyldianiline (1) followed by the reaction with bromo-4-(bromomethyl)benzene afforded the corresponding 4-((4-bromobenzyl)selanyl)aniline (2) in 85% yield.
Saad Shaaban +11 more
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Inorganics, 2022 Novel methyl anthranilate-based organoselenocyanate hybrids were developed, and their structures were confirmed by the state-of-the-art spectroscopic techniques.
Batool Al-Abdallah +2 more
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Molecules, 2023 Selenium is an essential trace element in living organisms, and is present in selenoenzymes with antioxidant activity, like glutathione peroxidase (GPx) and thioredoxin reductase (TrxR).
João M. Anghinoni +7 more
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